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    Afuco™ Anti-ST8SIA1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-764) (CAT#: AFC-TAB-764)

    This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant mouse monoclonal antibody expressed in CHO binding to human ganglioside GD3. It is a mouse monoclonal antibody investigated for the treatment of small cell lung carcinoma in combination with BCG vaccination.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Cerebral cortex
    Figure 1 Cerebral cortex
    (Neuronal cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26775/55367_B_9_5.jpg
    Figure 2 Lung
    Figure 2 Lung
    (Alveolar cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Macrophages
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26775/55367_A_2_4.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Glandular cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Peripheral nerve/ganglion
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26775/55367_A_9_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Hepatocytes
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26775/55367_A_9_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in tubules
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26775/55367_A_7_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Cells in seminiferous ducts
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Leydig cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26775/55367_A_4_6.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26775/55367_A_8_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enhanced (AF22, ASC TERT1, hTERT-RPE1, RPTEC TERT1, SK-MEL-30, WM-115)
    Figure 8 RNA cell line category: Cell line enhanced (AF22, ASC TERT1, hTERT-RPE1, RPTEC TERT1, SK-MEL-30, WM-115)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000111728-ST8SIA1

    Specifications

    • Immunogen
    • The details of the immunogen for this antibody are not available.
    • Host Species
    • Mouse
    • Derivation
    • Mouse
    • Type
    • ADCC enhanced antibody
    • Species Reactivity
    • Human
    • Applications
    • ELISA, FC, IP, FuncS, IF, Neut
    • Conjugate
    • Unconjugated
    • Generic Name
    • Mitumomab
    • Related Disease
    • Melanoma

    Product Property

    • Purity
    • >95% by SDS-PAGE
    • Storage
    • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • ST8 alpha-N-acetyl-neuraminide alpha-2, 8-sialyltransferase 1; sialyltransferase 8 (alpha N acetylneuraminate: alpha 2, 8 sialytransferase, GD3 synthase) A, SIAT8, SIAT8A; alpha-N-acetylneuraminide alpha-2, 8-sialyltrans

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Mitumomab"

    DrugMonitor™ Anti-Mitumomab Antibody (VS-1224-YC754)
    Mitumomab is an anti-BEC-2 monoclonal antibody derived from mice, previously studied for small cell lung carcinoma treatment in combination with BCG vaccination. The DrugMonitor™ Anti-Mitumomab Antibody (VS-1224-YC754) is an anti-drug antibody (ADA) against Mitumomab. This drug-based antibody is raised in mice immunized with the Mitumomab. The anti-Mitumomab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Mitumomab in samples.

    See other products for "ST8SIA1"

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