Anti-STEAP1 (clone 120.545) Recombinant Antibody Coupled Liposome (VS-1024-FY306) (CAT#: VS-1024-FY306)

• Potential Clinical Applications
• Prostate cancer

• Clone
• 120.545

• Antibody Type
• IgG

• Antibody Host
• Mouse

• Antibody Reactivity
• Human

• Antibody Description
• This antibody is a recombinant mouse monoclonal that was specifically engineered to target and interact with STEAP1. Its design involves crafting a highly selective affinity for STEAP1, a protein implicated in various cellular processes. By binding to this target, the antibody aims to facilitate research and therapeutic applications related to STEAP1's role in diseases.

• Storage
• See in the COA

• Storage Shelf Time
• See in the COA

• Target
• STEAP1

• Introduction
• This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions.

• Alternative Names
• STEAP; PRSS24; STEAP1; STEAP family member 1

• Full Name
• Metalloreductase STEAP1

• Gene ID
• 26872

• UniProt ID
• Q9UHE8

• Sequence Similarities
• Belongs to the STEAP family.

• Cellular Localization
• Endosome membrane

• Post Translation Modifications
• Modification sites at PhosphoSitePlus ( Q9UHE8 )
  Modification sites at neXtProt

• Protein Refseq
• NP_036581.1

• Function
• Does not function as a metalloreductase due to the absence of binding sites for the electron-donating substrate NADPH.
  Promotes Fe(3+) reduction when fused to the NADPH-binding domain of STEAP4.

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