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    Mouse Anti-STMN1 Recombinant Antibody (VS3-CJ706) (CAT#: VS3-CJ706)

    This product is a mouse antibody that recognizes human STMN1.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line A-431
    Figure 1 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10107/if_selected.jpg
    Normal Tissue
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Glial cells
    Staining: Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Neuronal cells
    Staining: Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous nuclear
    Neuropil
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/68438/168896_B_8_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Goblet cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Mucosal lymphoid cells
    Staining: Medium
    Intensity: Strong
    Quantity: <25%
    Peripheral nerve/ganglion
    Staining: High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/68438/168896_A_8_3.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Collecting ducts
    Staining: Medium
    Intensity: Strong
    Quantity: <25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/68438/168896_A_7_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Cells in seminiferous ducts
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear
    Leydig cells
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/68438/168896_A_6_6.jpg
    Figure 6 Lymph node
    Figure 6 Lymph node
    (Germinal center cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/68438/168896_A_7_8.jpg
    RNA Expression
    Figure 7 RNA cell line category: Cell line enhanced (MOLT-4)
    Figure 7 RNA cell line category: Cell line enhanced (MOLT-4)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000117632-STMN1/subcellular

    Specifications

    • Immunogen
    • KLH-conjugated synthetic peptide encompassing a sequence within human STMN1
    • Host Species
    • Mouse
    • Type
    • Mouse IgG2b
    • Specificity
    • Human STMN1
    • Species Reactivity
    • Human
    • Applications
    • WB, IHC
    • Conjugate
    • Unconjugated

    Product Property

    • Purification
    • Immunogen affinity chromatography
    • Purity
    • >95% as determined by SDS-PAGE
    • Format
    • Liquid
    • Buffer
    • 50% Glycerol, 0.2% BSA, PBS.
    • Preservative
    • 0.01% Sodium Azide
    • Storage
    • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Shipped at 4°C

    Applications

    • Application Notes
    • This antibody has been tested for use in Western Blot (1:500-1:1000), Immunohistochemistry (1:100-1:300).

    Target

    • Alternative Names
    • Lag; SMN; OP18; PP17; PP19; PR22; LAP18; C1orf215
    • Sequence Similarities
    • Belongs to the stathmin family.
    • Cellular Localization
    • Cytoplasm, Cytoskeleton, Microtubule
    • Post Translation Modifications
    • Many different phosphorylated forms are observed depending on specific combinations among the sites which can be phosphorylated. MAPK is responsible for the phosphorylation of stathmin in response to NGF. Phosphorylation at Ser-16 seems to be required for neuron polarization (By similarity).
      Phosphorylation at Ser-63 reduces tubulin binding 10-fold and suppresses the MT polymerization inhibition activity.
    • Function
    • Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity).

    Recommended Products

    Secondary Antibody

    Recommended Dilution Buffer

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "STMN1"

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    IgG Antibody Products Rabbit Monoclonal Antibody Products Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
    CAT Product Name Application Type
    MOB-3537z Mouse Anti-STMN1 Recombinant Antibody (clone 11H12) WB, FC, ICC, IF, IHC Mouse IgG2b
    ZG-0110C Mouse Anti-STMN1 Recombinant Antibody (clone ABT-Stathmin) IHC-P, IF Mouse IgG
    ZG-0111C Mouse Anti-STMN1 Recombinant Antibody (clone PT2148) IHC-P, IF Mouse IgG
    VS3-WK795 Rabbit Anti-STMN1 Recombinant Antibody (clone SS0453) WB, ICC, IHC, IP, FC Rabbit IgG
    VS3-FY1409 Recombinant Mouse Anti-STMN1 Antibody (clone 10D6-2D10-2F9) IHC-P Mouse IgG2b

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