SmartAb™ Recombinant Anti-TAA pH-dependent Antibody (Clone B6.2)
CAT#: VS-0825-YC319
The anti-TAA pH-dependent antibody (clone B6.2) is a pH-responsive antibody engineered to target a human Tumor-Associated Antigen (TAA). This pH-switched monoclonal antibody (mAb) was developed by incorporating histidine residues into its variable regions, which results in pH-biased binding to the TAA. By leveraging the natural pH variations in different tissues and cellular compartments, this pH-responsive antibody facilitates precise targeting of the TAA on cells and tissues. A Tumor-Associated Antigen (TAA) is a broad term for antigens expressed on cancer cells. While not a single protein, TAAs are a key focus of cancer immunotherapy as they can be targeted to specifically destroy tumor cells while minimizing harm to healthy tissues.
Specifications
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- IgG1 kappa (combining the mouse antibody's antigen-binding variable regions with a human IgG1 constant region)
- Specificity
- Human TAA
- Species Reactivity
- Human
- Clone
- B6.2
- Applications
- ELISA, WB
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95%, determined by SDS-PAGE and SEC-HPLC
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- For short-term storage, keep it at 4°C for up to two weeks. For long-term storage, divide the solution into aliquots and freeze them at -20°C or below.
Target
- Alternative Names
- TAA; Tumor-associated antigen
- Long Name
- Tumor-associated antigen
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone B6.2"
- CAT
- Product Name
See other products for "TAA"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0312CQ | Human Anti-TAA Recombinant Antibody (clone B6.2) | ELISA, WB | Chimeric (mouse/human) IgG1, κ |
| FAMAB-0313CQ | Human Anti-TAA Recombinant Antibody (clone chL6) | ELISA, IHC | Chimeric (mouse/human) IgG1, κ |
| FAMAB-0314CQ | Mouse Anti-TAA Recombinant Antibody (clone L6) | ELISA, IHC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0312CQ-F(E) | Human Anti-TAA Recombinant Antibody (clone B6.2); Fab Fragment | ELISA, WB | Human Fab |
| FAMAB-0313CQ-F(E) | Human Anti-TAA Recombinant Antibody (clone chL6); Fab Fragment | ELISA, IHC | Chimeric (mouse/human) Fab |
| FAMAB-0314CQ-F(E) | Mouse Anti-TAA Recombinant Antibody (clone L6); Fab Fragment | ELISA, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0312CQ-S(P) | Human Anti-TAA Recombinant Antibody (clone B6.2); scFv Fragment | ELISA, WB | Human scFv |
| FAMAB-0314CQ-S(P) | Mouse Anti-TAA Recombinant Antibody (clone L6); scFv Fragment | ELISA, IHC | Mouse scFv |
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