Rabbit Anti-TBL1XR1 Recombinant Antibody (VS13-YC1141) (CAT#: VS13-YC1141)

The Rabbit Anti-TBL1XR1 Recombinant Antibody is specific for human, mouse and rat TBL1XR1. TBL1XR1 encodes a WD40 repeat protein linked to transcription activation and linked to chromosome translocations in tumors and some autism spectrum disorders. The anti-TBL1XR1 antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry (1/50-1/100), Immunofluorescence (1/50-1/200).

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Specifications

  • Immunogen
  • Recombinant human TBLR1.
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat TBL1XR1
  • Species Reactivity
  • Human, Mouse, Rat
  • Applications
  • WB, IHC-P, ICC, IF
  • Conjugate
  • NONE

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Affinity Chromatography purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
  • Preservative
  • 0.01% Sodium azide
  • Storage
  • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Shipping with ice pack.

Applications

  • Application Notes
  • Western blot (WB): 1/500-1/1000
    Immunohistochemistry (IHC): 1/50-1/100
    Immunofluorescence (IF): 1/50-1/200

Target

  • Alternative Names
  • Transducin Beta Like 1 X-Linked Receptor 1; Nuclear Receptor Corepressor/HDAC3 Complex Subunit TBLR1; TBL1-Related Protein 1; TBLR1; IRA1; Nuclear Receptor Co-Repressor/HDAC3 Complex Subunit; F-Box-Like/WD Repeat-Containing Protein TBL1XR1;
  • Long Name
  • Transducin Beta Like 1 X-Linked Receptor 1
  • Sequence Similarities
  • Belongs to the WD repeat EBI family.
  • Cellular Localization
  • Nucleus
  • Function
  • F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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