Mouse Anti-TBL1XR1 Recombinant Antibody (VS3-FY2888)

CAT#: VS3-FY2888

The anti-TBL1XR1 antibody is a mouse recombinant monoclonal antibody that has been specifically designed to target the human, mouse TBL1XR1 protein, a calculated molecular weight of the protein is about 55.5 kDa. This monoclonal antibody proves valuable in disease research related to Pierpont Syndrome and Intellectual Developmental Disorder, Autosomal Dominant 41.

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human and Mouse TBL1XR1
  • Species Reactivity
  • Human, Mouse
  • Applications
  • Western Blot, Immunohistochemistry, Flow cytometry, ELISA
  • Conjugate
  • Unconjugated, FITC
  • MW
  • The molecular weight of the target protein is approximately 55.5 kDa.
  • Related Disease
  • Pierpont Syndrome and Intellectual Developmental Disorder, Autosomal Dominant 41

Product Property

  • Clonality
  • Monoclonal Antibody
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/2000
    Immunohistochemistry: 1/50-1/200
    Flow cytometry: 1/50-1/200
    ELISA: 1/1000-1/10000

Target

  • Alternative Names
  • Transducin Beta Like 1 X-Linked Receptor 1; Nuclear Receptor Corepressor/HDAC3 Complex Subunit TBLR1; TBL1-Related Protein 1; TBLR1; IRA1; Nuclear Receptor Co-Repressor/HDAC3 Complex Subunit; F-Box-Like/WD Repeat-Containing Protein TBL1XR1
  • Sequence Similarities
  • Belongs to the WD repeat EBI family.
  • Cellular Localization
  • Nucleus
  • Function
  • F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.
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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

Secondary Antibody

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