Mouse Anti-TBL1XR1 Recombinant Antibody (VS3-FY2888) (CAT#: VS3-FY2888)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Human and Mouse TBL1XR1

• Species Reactivity
• Human, Mouse

• Applications
• Western Blot, Immunohistochemistry, Flow cytometry, ELISA

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 55.5 kDa.

• Related Disease
• Pierpont Syndrome and Intellectual Developmental Disorder, Autosomal Dominant 41

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/2000
  Immunohistochemistry: 1/50-1/200
  Flow cytometry: 1/50-1/200
  ELISA: 1/1000-1/10000

• Alternative Names
• Transducin Beta Like 1 X-Linked Receptor 1; Nuclear Receptor Corepressor/HDAC3 Complex Subunit TBLR1; TBL1-Related Protein 1; TBLR1; IRA1; Nuclear Receptor Co-Repressor/HDAC3 Complex Subunit; F-Box-Like/WD Repeat-Containing Protein TBL1XR1

• Gene ID
• 79718

• UniProt ID
• Q9BZK7

• Sequence Similarities
• Belongs to the WD repeat EBI family.

• Cellular Localization
• Nucleus

• Protein Refseq
• NP_001308122.1; NP_001308123.1; NP_001308124.1

• Function
• F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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