AbPlus™ Anti-TNFRSF18 Magnetic Beads (VS-0424-XY257)
CAT#: VS-0424-XY257
The AbPlus Anti-TNFRSF18 Magnetic Beads (VS-0424-XY257) is an innovative affinity resin which is bound with anti-TNFRSF18 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of TNFRSF18 protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human spleen
Immunohistochemical staining of human spleen shows moderate cytoplasmic positivity in red pulp and cells in white pulp.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_B_9_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_7_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_5_6.jpg
Normal Tissue
Figure 6 Bone marrow
Hematopoietic cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_B_4_4.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8025/24709_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Group enriched (RPMI-8226, SCLC-21H)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186891-TNFRSF18
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-TNFRSF18 specific antibody
- Target
- TNFRSF18
- Immunogen
- Human AITR-GST fusion protein
- Target Species
- Human
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Alternative Names
- TNFRSF18; tumor necrosis factor receptor superfamily, member 18; AITR; GITR; CD357; GITR-D; tumor necrosis factor receptor superfamily member 18; activation-inducible TNFR family receptor; glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation-inducible protein
- Gene ID
- 8784
- UniProt ID
- Q9Y5U5
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Datasheet
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COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-629CL | Human Anti-TNFRSF18 Recombinant Antibody (TAB-629CL) | Activ | Human IgG |
| TAB-098CQ | Human Anti-TNFRSF18 Recombinant Antibody (TAB-098CQ) | ELISA, FC, WB | Humanized antibody |
| TAB-098CQ-S(P) | Human Anti-TNFRSF18 Recombinant Antibody; scFv Fragment (TAB-098CQ-S(P)) | ELISA, FC, WB | Human scFv |
| TAB-098CQ-F(E) | Human Anti-TNFRSF18 Recombinant Antibody; Fab Fragment (TAB-098CQ-F(E)) | ELISA, FC, WB | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-097CQ | Mouse Anti-TNFRSF18 Recombinant Antibody (TAB-097CQ) | ELISA, FC, WB | Mouse IgG |
| TAB-097CQ-S(P) | Mouse Anti-TNFRSF18 Recombinant Antibody; scFv Fragment (TAB-097CQ-S(P)) | ELISA, FC, WB | Mouse scFv |
| TAB-104CQ-S(P) | Mouse Anti-TNFRSF18 Recombinant Antibody; scFv Fragment (TAB-104CQ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-097CQ-F(E) | Mouse Anti-TNFRSF18 Recombinant Antibody; Fab Fragment (TAB-097CQ-F(E)) | ELISA, FC, WB | Mouse Fab |
| TAB-104CQ-F(E) | Mouse Anti-TNFRSF18 Recombinant Antibody; Fab Fragment (TAB-104CQ-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-105CQ | Human Anti-TNFRSF18 Recombinant Antibody (TAB-105CQ) | ELISA, FC | Chimeric (mouse/human) IgG |
| TAB-105CQ-S(P) | Mouse Anti-TNFRSF18 Recombinant Antibody; scFv Fragment (TAB-105CQ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-105CQ-F(E) | Human Anti-TNFRSF18 Recombinant Antibody; Fab Fragment (TAB-105CQ-F(E)) | ELISA, FC | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-099CQ-S(P) | Human Anti-TNFRSF18 Recombinant Antibody; scFv Fragment (TAB-099CQ-S(P)) | ELISA, FC | Human scFv |
| TAB-100CQ-S(P) | Human Anti-TNFRSF18 Recombinant Antibody; scFv Fragment (TAB-100CQ-S(P)) | ELISA, FC | Human scFv |
| TAB-101CQ-S(P) | Human Anti-TNFRSF18 Recombinant Antibody; scFv Fragment (TAB-101CQ-S(P)) | ELISA, FC | Human scFv |
| TAB-102CQ-S(P) | Human Anti-TNFRSF18 Recombinant Antibody; scFv Fragment (TAB-102CQ-S(P)) | ELISA, FC | Human scFv |
| TAB-103CQ-S(P) | Human Anti-TNFRSF18 Recombinant Antibody; scFv Fragment (TAB-103CQ-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2134CQ | Mouse Anti-TNFRSF18 Recombinant Antibody (NEUT-2134CQ) | FC, Neut, WB | Mouse IgG1 |
| NEUT-2139CQ | Mouse Anti-TNFRSF18 Recombinant Antibody (clone CBL066) | Neut, FC, WB | Mouse IgG1 |
| NEUT-2140CQ | Mouse Anti-TNFRSF18 Recombinant Antibody (clone CBL189) | FC, Neut | Mouse IgG1 |
| NEUT-2141CQ | Mouse Anti-TNFRSF18 Recombinant Antibody (clone MM0312-4Q25) | Neut, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2135CQ | Mouse Anti-TNFRSF18 Recombinant Antibody (clone CBL318) | Block, FC, ELISA, WB, CyTOF | Mouse IgG1 |
| NEUT-2136CQ | Rat Anti-Tnfrsf18 Recombinant Antibody (clone DTA-1) | Block, FC, IP | Rat IgG2b |
| NEUT-2137CQ | Rat Anti-Tnfrsf18 Recombinant Antibody (NEUT-2137CQ) | Block, FC | Rat IgG2 |
| NEUT-2138CQ | Mouse Anti-Tnfrsf18 Recombinant Antibody (clone YGITR765) | FC, Block | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0052-LS | Human Anti-TNFRSF18 Recombinant Antibody (HPAB-0052-LS) | ELISA, FC, FuncS | Humanized IgG1, κ |
| HPAB-0053-LS | Human Anti-TNFRSF18 Recombinant Antibody (HPAB-0053-LS) | ELISA, FC, FuncS | Humanized IgG1, κ |
| HPAB-0440-WJ | Mouse Anti-TNFRSF18 Recombinant Antibody (HPAB-0440-WJ) | ELISA, FC, IHC | Mouse IgG |
| HPAB-0441-WJ | Mouse Anti-TNFRSF18 Recombinant Antibody (HPAB-0441-WJ) | ELISA, FC, IHC | Mouse IgG |
| VS-0723-WK189 | Rabbit Anti-TNFRSF18 Recombinant Antibody (VS-0723-WK189) | ELISA, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0052-LS-F(E) | Human Anti-TNFRSF18 Recombinant Antibody; Fab Fragment (HPAB-0052-LS-F(E)) | ELISA | Humanized Fab |
| HPAB-0053-LS-F(E) | Human Anti-TNFRSF18 Recombinant Antibody; Fab Fragment (HPAB-0053-LS-F(E)) | ELISA | Humanized Fab |
| HPAB-2682LY-F(E) | Mouse Anti-TNFRSF18 Recombinant Antibody; Fab Fragment (HPAB-2682LY-F(E)) | ELISA, IHC, ECL, WB, IP, FC, IF, RIA | Mouse Fab |
| HPAB-2683LY-F(E) | Mouse Anti-TNFRSF18 Recombinant Antibody; Fab Fragment (HPAB-2683LY-F(E)) | ELISA, IHC, ECL, WB, IP, FC, IF, RIA | Mouse Fab |
| HPAB-2684LY-F(E) | Mouse Anti-TNFRSF18 Recombinant Antibody; Fab Fragment (HPAB-2684LY-F(E)) | ELISA, IHC, ECL, WB, IP, FC, IF, RIA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0052-LS-S(P) | Human Anti-TNFRSF18 Recombinant Antibody; scFv Fragment (HPAB-0052-LS-S(P)) | ELISA | Human scFv |
| HPAB-0053-LS-S(P) | Human Anti-TNFRSF18 Recombinant Antibody; scFv Fragment (HPAB-0053-LS-S(P)) | ELISA | Human scFv |
| HPAB-0198-WJ-S(P) | Human Anti-TNFRSF18 Recombinant Antibody (clone pab1876); scFv Fragment | ELISA | Human scFv |
| HPAB-0440-WJ-S(P) | Mouse Anti-TNFRSF18 Recombinant Antibody; scFv Fragment (HPAB-0440-WJ-S(P)) | ELISA, FC, IHC | Mouse scFv |
| HPAB-0441-WJ-S(P) | Mouse Anti-TNFRSF18 Recombinant Antibody; scFv Fragment (HPAB-0441-WJ-S(P)) | ELISA, FC, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-XY45 | Human Anti-TNFRSF18 Agonistic Antibody (VS-0724-XY45) | ELISA, Agonistic assays | Human IgG1 |
| VS-0724-XY46 | Rabbit Anti-Tnfrsf18 Agonistic Antibody (VS-0724-XY46) | FC, WB, IP, Agonistic assays | Rabbit IgG, lambda |
| VS-0724-XY47 | Rat Anti-Tnfrsf18 Agonistic Antibody (clone DTA-1) | FC, WB, IP, Agonistic assays | Rat IgG2a, lambda |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY220 | CytoStream™ Mouse Anti-TNFRSF18 Recombinant Antibody (VS-0225-XY220) | FC | Mouse IgG2b, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC273 | Recombinant Anti-TNFRSF18 Vesicular Antibody, EV Displayed (VS-0425-YC273) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7377 | Anti-TNFRSF18 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7378 | Anti-Mouse TNFRSF18 Immunohistochemistry Kit | IHC |
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