Recombinant Human Anti-TNFRSF1A Single Domain Antibody (HPAB-J0305-YC)
CAT#: HPAB-J0305-YC
Provided are single variable domains (dAbs) which bind TNFRl and inhibit its functional activity in cell assays, however these domain antibodies should not (substantially) compete with TNFαfor binding to TNFRl.
Tested Data
Gene Expression
WB
Figure 2 Anti-TNFRSF1A Single Domain Antibody (HPAB-J0305-YC) in WB
Western blot analysis of HPAB-J0305-YC was performed by loading Human TNFR1 / CD120a / TNFRSF1A Protein, Fc Tag.
HPAB-J0305-YC incubation concentration: 2 ng/μL.
The secondary antibody: HRP-Anti-His tag
Lane 1: Reducing Antigen (0.1μg)
Lane 2: Reducing Antigen (0.3μg)
Lane 3: Reducing Antigen (0.6μg)
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Normal Tissue
Figure 1 Cerebral cortex
Glial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10309/25571_B_7_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10309/25571_A_7_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10309/25571_A_9_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10309/25571_A_6_6.jpg
Normal Tissue
Figure 5 Lymph node
Germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10309/25571_A_9_8.jpg
RNA Expression
Figure 6 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000067182-TNFRSF1A
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Specifications
- Host Species
- Human
- Type
- Human VHH
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- HPAB-J0305-YC
- Applications
- ELISA, Inhibition
Product Property
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles
Target
- Alternative Names
- TNF Receptor Superfamily Member 1A; TNF-R1; TNF-RI; TNFR-I; TNFR1; TNFAR; P60; P55; Tumor Necrosis Factor Receptor Superfamily, Member 1A; Tumor Necrosis Factor Receptor Superfamily Member 1A; Tumor Necrosis Factor Receptor 1A Isoform Beta; Tumor Necrosis Factor Binding Protein 1; Tumor Necrosis Factor Receptor Type 1; Tumor Necrosis Factor Receptor Type I
- Gene ID
- 7132
- UniProt ID
- P19438
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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|---|---|---|---|
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| HPAB-J0307-YC | Recombinant Human Anti-TNFRSF1A Single Domain Antibody (HPAB-J0307-YC) | ELISA, Inhib | Human VHH |
| HPAB-J0308-YC | Recombinant Human Anti-TNFRSF1A Single Domain Antibody (HPAB-J0308-YC) | ELISA, Inhib | Human VHH |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-106CQ | Mouse Anti-TNFRSF1A Recombinant Antibody (TAB-106CQ) | WB, FC, IHC | Mouse IgG2a, κ |
| TAB-106CQ-S(P) | Mouse Anti-TNFRSF1A Recombinant Antibody; scFv Fragment (TAB-106CQ-S(P)) | ELISA, FC, Neut | Mouse scFv |
| TAB-106CQ-F(E) | Mouse Anti-TNFRSF1A Recombinant Antibody; Fab Fragment (TAB-106CQ-F(E)) | ELISA, FC, Neut | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-107CQ | Human Anti-TNFRSF1A Recombinant Antibody (TAB-107CQ) | ELISA, FC, Neut | Humanized antibody |
| TAB-107CQ-S(P) | Human Anti-TNFRSF1A Recombinant Antibody; scFv Fragment (TAB-107CQ-S(P)) | ELISA, FC, Neut | Humanized scFv |
| TAB-107CQ-F(E) | Human Anti-TNFRSF1A Recombinant Antibody; Fab Fragment (TAB-107CQ-F(E)) | ELISA, FC, Neut | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| NEUT-2144CQ | Hamster Anti-Tnfrsf1a Recombinant Antibody (clone CBL802) | WB, IP, Neut | Hamster IgG |
| NEUT-2145CQ | Hamster Anti-Tnfrsf1a Recombinant Antibody (clone CBL178) | FC, ELISA, WB, IP, Neut | Hamster IgG |
| NEUT-2146CQ | Mouse Anti-TNFRSF1A Recombinant Antibody (clone 5D31) | Neut, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3613 | Rabbit Anti-TNFRSF1A Recombinant Antibody (clone DS3613AB) | WB, FC | Rabbit IgG |
| MOR-3614 | Rabbit Anti-Tnfrsf1a Recombinant Antibody (clone DS3614AB) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-097LC | Rat Anti-Tnfrsf1a Recombinant Antibody (clone HM102) | IP, IHC, FC | Rat IgG2a |
| VS-0724-XY48 | Mouse Anti-TNFRSF1A Agonistic Antibody (clone MR1-2) | FC, IHC, IA, Agonistic assays | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1695LY-S(P) | Human Anti-TNFRSF1A Recombinant Antibody; scFv Fragment (HPAB-1695LY-S(P)) | ELISA, FC, Inhib | Human scFv |
| HPAB-1696LY-S(P) | Human Anti-TNFRSF1A Recombinant Antibody; scFv Fragment (HPAB-1696LY-S(P)) | ELISA, FC, Inhib | Human scFv |
| HPAB-N0275-YC-S(P) | Human Anti-TNFRSF1A Recombinant Antibody; scFv Fragment (HPAB-N0275-YC-S(P)) | ELISA | Human scFv |
| HPAB-1441-FY-S(P) | Human Anti-TNFRSF1A Recombinant Antibody; scFv Fragment (HPAB-1441-FY-S(P)) | ELISA, Inhib, IF, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1695LY | Human Anti-TNFRSF1A Recombinant Antibody (HPAB-1695LY) | ELISA, FC, Inhib, FuncS | Humanized IgG |
| HPAB-1696LY | Human Anti-TNFRSF1A Recombinant Antibody (HPAB-1696LY) | ELISA, FC, Inhib, FuncS | Humanized IgG |
| HPAB-N0275-YC | Human Anti-TNFRSF1A Recombinant Antibody (HPAB-N0275-YC) | ELISA | Human IgG |
| MOB-111LC | Mouse Anti-TNFRSF1A Recombinant Antibody (MOB-111LC) | FC | Mouse IgG1 |
| VS7-0425-WR1019 | Mouse Anti-TNFRSF1A Recombinant Antibody (clone 2G11C9) | ICC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1695LY-F(E) | Human Anti-TNFRSF1A Recombinant Antibody; Fab Fragment (HPAB-1695LY-F(E)) | ELISA, FC, Inhib | Humanized Fab |
| HPAB-1696LY-F(E) | Human Anti-TNFRSF1A Recombinant Antibody; Fab Fragment (HPAB-1696LY-F(E)) | ELISA, FC, Inhib | Humanized Fab |
| HPAB-N0275-YC-F(E) | Human Anti-TNFRSF1A Recombinant Antibody; Fab Fragment (HPAB-N0275-YC-F(E)) | ELISA | Human Fab |
| HPAB-1441-FY-F(E) | Human Anti-TNFRSF1A Recombinant Antibody; Fab Fragment (HPAB-1441-FY-F(E)) | ELISA, Inhib, IF, FC | Human Fab |
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