Mouse Anti-TP63 Monoclonal Antibody (VS7-0425-WR1038)
CAT#: VS7-0425-WR1038
This product is a mouse IgG antibody that binds to human TP63. The antibody can be used for WB, IHC-P, IF, and ELISA assays. It cross reacts with mouse, rat, and monkey.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RT4
Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6289/1843_E1_9_cr5af96f44b42f8_selected.jpg
Normal Tissue
Figure 2 Skin 1
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6288/19019_B_7_1_val_selected.jpg
Normal Tissue
Figure 3 Skin
Cells in basal layer Staining: High Intensity: Strong Quantity:>75% Cells in granular layer Staining: Low Intensity: Moderate Quantity: <25% Cells in spinous layer Staining: High Intensity: Strong Quantity: 75%-25% Eccrine glands Staining: High Intensity: Strong Quantity: 75%-25% Hair follicles Staining: High Intensity: Strong Quantity: 75%-25% Sebaceous glands Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/83/860_B_9_1.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Non-germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/83/860_A_7_8.jpg
Normal Tissue
Figure 5 Testis
Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/83/860_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (HaCaT, HBEC3-KT, hTCEpi, hTERT-HME1, RT4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000073282-TP63
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Specifications
- Immunogen
- Synthetic human p63 peptide
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human TP63
- Species Reactivity
- Human, Mouse, Rat, Monkey
- Molecule Class
- Tumor Suppressor
- Applications
- WB, IHC-P, IF, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Acro-dermato-ungual-lacrimal-tooth syndrome (ADULT syndrome); Ankyloblepharon-ectodermal defects-cleft lip/palate (AEC); Ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); Split-hand/foot malformation 4 (SHFM4); Limb-mammary syndrome (LMS); Rapp-Hodgkin syndrome (RHS); Orofacial cleft 8 (OFC8); Premature ovarian failure 21 (POF21)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- 1 mg/ml
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry: 1:200 - 1:1000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- AIS; KET; LMS; NBP; RHS; p40; p51; p63; EEC3; OFC8; p73H; p73L; SHFM4; TP53L; TP73L; p53CP; TP53CP; B(p51A); B(p51B)
- Gene ID
- 8626
- UniProt ID
- Q9H3D4
- Long Name
- Tumor protein p63
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Isopeptide bond; Ubl conjugation
- Protein Refseq
- NP_001108450.1
- Function
- Activator; Developmental protein; DNA-binding
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Reconstitution Buffer
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "TP63"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3647 | Rabbit Anti-TP63 Recombinant Antibody (clone DS3647AB) | ICC, IF, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1156-CN | Rabbit Anti-TP63 Recombinant Antibody (clone CBACN-419) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-QX1153 | Mouse Anti-TP63 Recombinant Antibody (clone 3C7-9B7-9B10) | WB, IHC | Mouse IgG1 |
| VS3-QX1154 | Mouse Anti-TP63 Recombinant Antibody (clone 5G6-10A9-2A4) | WB | Mouse IgG1 |
| VS3-QX1155 | Mouse Anti-TP63 Recombinant Antibody (clone 8H1-1G8-9A6) | WB | Mouse IgG1 |
| VS3-QX1156 | Mouse Anti-TP63 Recombinant Antibody (clone 1D6-3C3-4F7) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0411-YJ-S(P) | Mouse Anti-TP63 Recombinant Antibody; scFv Fragment (HPAB-0411-YJ-S(P)) | ELISA, WB, DB, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0411-YJ-F(E) | Mouse Anti-TP63 Recombinant Antibody; Fab Fragment (HPAB-0411-YJ-F(E)) | ELISA, WB, DB, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX1161 | Mouse Anti-TP63 Recombinant Antibody (clone 603CT12.4.3) | WB | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2332 | Anti-TP63 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7448 | Anti-Mouse TP63 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7447 | Anti-Human TP63 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7449 | Anti-Rat TP63 Immunohistochemistry Kit | IHC |
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