Mouse Anti-TP63 Monoclonal Antibody (VS7-0425-WR1038) (CAT#: VS7-0425-WR1038)
This product is a mouse IgG antibody that binds to human TP63. The antibody can be used for WB, IHC-P, IF, and ELISA assays. It cross reacts with mouse, rat, and monkey.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RT4
(Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6289/1843_E1_9_cr5af96f44b42f8_selected.jpg
(Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6289/1843_E1_9_cr5af96f44b42f8_selected.jpg
Figure 2 Skin 1
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6288/19019_B_7_1_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6288/19019_B_7_1_val_selected.jpg
Figure 3 Skin
(Cells in basal layer Staining: High Intensity: Strong Quantity:>75% Cells in granular layer Staining: Low Intensity: Moderate Quantity: <25% Cells in spinous layer Staining: High Intensity: Strong Quantity: 75%-25% Eccrine glands Staining: High Intensity: Strong Quantity: 75%-25% Hair follicles Staining: High Intensity: Strong Quantity: 75%-25% Sebaceous glands Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/83/860_B_9_1.jpg
(Cells in basal layer Staining: High Intensity: Strong Quantity:>75% Cells in granular layer Staining: Low Intensity: Moderate Quantity: <25% Cells in spinous layer Staining: High Intensity: Strong Quantity: 75%-25% Eccrine glands Staining: High Intensity: Strong Quantity: 75%-25% Hair follicles Staining: High Intensity: Strong Quantity: 75%-25% Sebaceous glands Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/83/860_B_9_1.jpg
Figure 4 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Non-germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/83/860_A_7_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Non-germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/83/860_A_7_8.jpg
Figure 5 Testis
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/83/860_A_6_6.jpg
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/83/860_A_6_6.jpg
Figure 6 RNA cell line category: Group enriched (HaCaT, HBEC3-KT, hTCEpi, hTERT-HME1, RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000073282-TP63
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000073282-TP63
Specifications
- Immunogen
- Synthetic human p63 peptide
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human TP63
- Species Reactivity
- Human, Mouse, Rat, Monkey
- Molecule Class
- Tumor Suppressor
- Applications
- WB, IHC-P, IF, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Acro-dermato-ungual-lacrimal-tooth syndrome (ADULT syndrome); Ankyloblepharon-ectodermal defects-cleft lip/palate (AEC); Ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); Split-hand/foot malformation 4 (SHFM4); Limb-mammary syndrome (LMS); Rapp-Hodgkin syndrome (RHS); Orofacial cleft 8 (OFC8); Premature ovarian failure 21 (POF21)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- 1 mg/ml
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry: 1:200 - 1:1000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- AIS; KET; LMS; NBP; RHS; p40; p51; p63; EEC3; OFC8; p73H; p73L; SHFM4; TP53L; TP73L; p53CP; TP53CP; B(p51A); B(p51B)
- Gene ID
- 8626
- UniProt ID
- Q9H3D4
- Long Name
- Tumor protein p63
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Isopeptide bond; Ubl conjugation
- Protein Refseq
- NP_001108450.1
- Function
- Activator; Developmental protein; DNA-binding
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1516CT | Recombinant Mouse anti-Human TP63 Monoclonal antibody (98D664) | WB | |
| MOB-0163F | Mouse Anti-TP63 Recombinant Antibody (MOB-0163F) | IHC-P, IF | Mouse IgG |
| MOB-0164F | Mouse Anti-TP63 Recombinant Antibody (MOB-0164F) | IHC-P, IF | Mouse IgG |
| MOB-0165F | Mouse Anti-TP63 Recombinant Antibody (MOB-0165F) | IHC-P, IF | Mouse IgG |
| MOB-0166F | Mouse Anti-TP63 Recombinant Antibody (clone 3F11) | WB, IHC | Mouse IgG |
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