Mouse Anti-TP63 Recombinant Antibody (clone 14D5E8F12)
CAT#: VS11-QX140
This product is a recombinant mouse antibody that recognizes the p40 peptide of the human TP63. This antibody can be used for the following applications: ELISA, IHC. P63 is a member of the p53 gene family, which plays an important role in the development, differentiation, and morphogenesis of various epithelial tissues, is of great significance for the development of the ectoderm during embryogenesis.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RT4
Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6289/1843_E1_9_cr5af96f44b42f8_selected.jpg
Normal Tissue
Figure 2 Skin 1
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6288/19019_B_7_1_val_selected.jpg
Normal Tissue
Figure 3 Skin
Cells in basal layer Staining: High Intensity: Strong Quantity:>75% Cells in granular layer Staining: Low Intensity: Moderate Quantity: <25% Cells in spinous layer Staining: High Intensity: Strong Quantity: 75%-25% Eccrine glands Staining: High Intensity: Strong Quantity: 75%-25% Hair follicles Staining: High Intensity: Strong Quantity: 75%-25% Sebaceous glands Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/83/860_B_9_1.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Non-germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/83/860_A_7_8.jpg
Normal Tissue
Figure 5 Testis
Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/83/860_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (HaCaT, HBEC3-KT, hTCEpi, hTERT-HME1, RT4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000073282-TP63
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Specifications
- Immunogen
- The p40 peptide comprising amino acids 4-19 (LENNAQTQFSEPQYTN) of the p63 protein
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human TP63
- Species Reactivity
- Human
- Clone
- 14D5E8F12
- Applications
- ELISA, IHC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (Please refer to the vial label for the specific concentration.)
- Buffer
- 0.2 μm filtered solution in PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C.
Target
- Alternative Names
- AIS; KET; LMS; NBP; RHS; p40; p51; p63; EEC3; OFC8; p73H; p73L; SHFM4; TP53L; TP73L; p53CP; TP53CP; B(p51A); B(p51B); tumor protein 63; amplified in squamous cell carcinoma; chronic ulcerative stomatitis protein; keratinocyte transcription factor KET; transformation-related protein 63; tumor protein p53-competing protein
- Gene ID
- 8626
- UniProt ID
- Q9H3D4
- Long Name
- Tumor protein 63
- Sequence Similarities
- Belongs to the p53 family.
- Cellular Localization
- Nucleoplasm
- Function
- Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "TP63"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3647 | Rabbit Anti-TP63 Recombinant Antibody (clone DS3647AB) | ICC, IF, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2104-CN | Rabbit Anti-TP63 Polyclonal Antibody (MRO-2104-CN) | WB, IHC | Rabbit IgG |
| MOB-0163F | Mouse Anti-TP63 Recombinant Antibody (MOB-0163F) | IHC-P, IF | Mouse IgG |
| ZG-0349C | Mouse Anti-TP63 Recombinant Antibody (ZG-0349C) | WB, IHC, ELISA | Mouse IgG |
| ZG-0605U | Rabbit Anti-TP63 Recombinant Antibody (clone 4B3) | ELISA, WB, IHC | Rabbit IgG |
| VS7-0425-WR1038 | Mouse Anti-TP63 Monoclonal Antibody (VS7-0425-WR1038) | WB, IHC-P, IF, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0411-YJ-S(P) | Mouse Anti-TP63 Recombinant Antibody; scFv Fragment (HPAB-0411-YJ-S(P)) | ELISA, WB, DB, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0411-YJ-F(E) | Mouse Anti-TP63 Recombinant Antibody; Fab Fragment (HPAB-0411-YJ-F(E)) | ELISA, WB, DB, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX1161 | Mouse Anti-TP63 Recombinant Antibody (clone 603CT12.4.3) | WB | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2332 | Anti-TP63 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7448 | Anti-Mouse TP63 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7447 | Anti-Human TP63 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7449 | Anti-Rat TP63 Immunohistochemistry Kit | IHC |
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