Rabbit Anti-TRPM8 Recombinant Antibody (clone R07-9G7) (CAT#: VS3-XY3532)
It is a recombinant rabbit antibody specific for TRPM8 (Transient receptor potential cation channel subfamily M member 8). This antibody specifically reacts with human and mouse TRPM8. It has been reported for use in Western Blot, Immunocytochemistry or Immunofluorescence. The recommended dilutions of Western Blot and Immunofluorescence is 1/500-1/1000 and 1/50-1/200.
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RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (GAMG, Karpas-707, RPTEC TERT1, SK-MEL-30, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000144481-TRPM8
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000144481-TRPM8
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse TRPM8
- Species Reactivity
- Human, Mouse
- Clone
- R07-9G7
- Applications
- WB, ICC, IF
- Related Disease
- Migraine Without Aura; Photokeratitis
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IF: 1/50-1/200
Target
- Alternative Names
- LTRPC6, LTrpC-6, TRPP8, trp-p8
- Gene ID
- 79054
- UniProt ID
- Q7Z2W7
- Long Name
- Transient receptor potential cation channel subfamily M member 8
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Glycosylation at Asn934 (NX_Q7Z2W7 [NX_Q7Z2W7-1])
Modification sites at PhosphoSitePlus (Q7Z2W7)
Glycosylation from GlyGen (Q7Z2W7) 2 sites, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_016860380.1; XP_011510112.1
- Function
- Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius.
Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH.
Involved in menthol sensation.
Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3697 | Rabbit Anti-TRPM8 Recombinant Antibody (clone DS3697AB) | ICC, WB | Rabbit IgG |
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