Mouse Anti-TUBB3 Monoclonal Antibody (VS7-0425-WR1071) (CAT#: VS7-0425-WR1071)
This product is a mouse IgG antibody that binds to human TUBB3. The antibody can be used for WB, IF, ICC, FC, and ELISA assays.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (A549, SCLC-21H, SH-SY5Y)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000258947-TUBB3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000258947-TUBB3
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human TUBB3
- Species Reactivity
- Human
- Molecule Class
- Beta Tubulin Protein
- Applications
- WB, IF, ICC, FC, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Fibrosis of extraocular muscles, congenital, 3A (CFEOM3A); Cortical dysplasia, complex, with other brain malformations 1 (CDCBM1)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- 1 mg/ml
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunofluorescence: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- TUBB3; TUBB4; Class III Beta-Tubulin; Tubulin Beta-3 Chain; FEOM3; CFEOM3A; BETA-4; Tubulin, Beta 3; Tubulin Beta-III
- Gene ID
- 10381
- UniProt ID
- Q13509
- Long Name
- Tubulin Beta 3 Class III
- Cellular Localization
- Cell projection; Cytoplasm; Cytoskeleton; Microtubule
- Post Translation Modifications
- Isopeptide bond; Phosphoprotein
- Protein Refseq
- NP_001184110.1
- Function
- Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:34996871).; Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms (PubMed:34996871).; Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:34996871).; TUBB3 plays a critical role in proper axon guidance and maintenance (PubMed:20074521).; Binding of NTN1/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (PubMed:28483977).; Plays a role in dorsal root ganglion axon projection towards the spinal cord (PubMed:28483977).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-408 | Human Anti-TUBB3 Recombinant Antibody (clone YC094); Fab Fragment | WB, ELISA, FuncS | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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