Mouse Anti-UPK3A Recombinant Antibody (VS3-CJ181) (CAT#: VS3-CJ181)
This product is a mouse antibody that recognizes UPK3A.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm & nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18415/1293_E3_1_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm & nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18415/1293_E3_1_selected.jpg
Figure 2 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18415/43816_A_9_5.jpg
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18415/43816_A_9_5.jpg
Figure 3 Urinary bladder
(Urothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18415/43816_A_6_5.jpg
(Urothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18415/43816_A_6_5.jpg
Figure 4 RNA cell line category: Group enriched (Hep G2, RT4)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100373-UPK3A
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100373-UPK3A
Specifications
- Immunogen
- KLH-conjugated synthetic peptide encompassing a sequence within human Uroplakin 3a
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human UPK3A
- Species Reactivity
- Human
- Applications
- IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Immunogen affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.2% BSA, PBS.
- Preservative
- 0.01% sodium azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- This antibody has been tested for use in Immunohistochemistry (1:100-1:300).
Target
- Alternative Names
- UPK3; Uroplakin-3a; UP3a; Uroplakin III; UPIII; UPIIIA
- Gene ID
- 7380
- UniProt ID
- O75631
- Sequence Similarities
- Belongs to the uroplakin-3 family.
- Cellular Localization
- Endoplasmic reticulum membrane
- Protein Refseq
- NP_001161046.1; NP_008884.1
- Function
- Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Related Resources
Bladder Cancer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "UPK3A"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2145CT | Recombinant Mouse anti-Human UPK3A Monoclonal antibody (TGJ-2) | IHC-Fr, IHC-P, WB | |
| ZG-0168C | Mouse Anti-UPK3A Recombinant Antibody (clone ABT-UPK3) | IHC-P, IF | Mouse IgG |
| VS3-FY1524 | Recombinant Mouse Anti-UPK3A Antibody (clone 5D9-7E3-2C10) | IHC-P | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3795 | Rabbit Anti-UPK3A Recombinant Antibody (clone DS3795AB) | IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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