Rabbit Anti-UQCRB Recombinant Antibody (clone R04-4F5) (CAT#: VS3-FY1931)

• Immunogen
• Recombinant human UQCRB protein

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human and Rat UQCRB

• Species Reactivity
• Human, Rat

• Clone
• R04-4F5

• Applications
• Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation

• MW
• The calculated weight of the target protein is approximately 14 kDa, while the observed molecular weight stands at 14 kDa.

• Related Disease
• Mitochondrial Complex Iii Deficiency, Nuclear Type 3 and Mitochondrial Complex Iii Deficiency, Nuclear Type 1

• Purification
• Affinity Purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/1000
  Immunohistochemistry: 1/50-1/100
  Immunoprecipitation: 1/20

• Alternative Names
• Ubiquinol-Cytochrome C Reductase Binding Protein; Ubiquinol-Cytochrome C Reductase, Complex III Subunit VI; Ubiquinol-Cytochrome C Reductase Complex 14 KDa Protein; Cytochrome B-C1 Complex Subunit 7; Complex III Subunit VII; Complex III Subunit 7; UQBP; QP-C

• Gene ID
• 7381

• UniProt ID
• P14927

• Sequence Similarities
• Belongs to the UQCRB/QCR7 family.

• Cellular Localization
• Membrane, Mitochondrion, Mitochondrion inner membrane

• Post Translation Modifications
• Ubiquitination at Lys12 and Lys29 (NX_P14927 [NX_P14927-1])
  Modification sites at PhosphoSitePlus (P14927)
  Glycosylation from GlyGen (P14927) 1 site, 1 O-linked glycan (1 site)

• Protein Refseq
• NP_001186904.1; NP_001241681.1; NP_006285.1

• Function
• The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-054CQ
• Goat Anti-Rabbit IgG Antibody, R-PE

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-055CQ
• Chicken Anti-Rabbit IgG (H&L) Antibody

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