AbPlus™ Anti-VCL Magnetic Beads (VS-0724-YC1063)
CAT#: VS-0724-YC1063
The AbPlus Anti-VCL Magnetic Beads (VS-0724-YC1063) is an innovative affinity resin which is bound with anti-VCL specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of VCL protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 Testis
Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2131/7209_A_6_6.jpg
Normal Tissue
Figure 2 Smooth muscle
Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2131/7209_B_4_7.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2131/7209_B_8_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2131/7209_A_7_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2131/7209_A_8_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2131/7209_A_7_5.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (BJ hTERT+, hTERT-RPE1)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000035403-VCL
❮
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-VCL specific antibody
- Target
- VCL
- Immunogen
- Recombinant human Vinculin fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
- Alternative Names
- Vinculin; Metavinculin; MV; Epididymis Luminal Protein 114; Meta-Vinculin; HEL114; CMD1W; CMH15; MVCL;
- Gene ID
- 7414
- UniProt ID
- P18206
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "VCL"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3635z | Mouse Anti-VCL Recombinant Antibody (clone 8G3) | WB, IHC, IF, FC, ELISA | Mouse IgG1 |
| MOB-2218CT | Recombinant Mouse anti-Human VCL Monoclonal antibody (TQN338) | ICC, IF, IHC-P, IP, WB | |
| MRO-1586-CN | Rabbit Anti-VCL Recombinant Antibody (clone JM42-43) | WB, IF, IP | Rabbit IgG |
| VS3-FY1540 | Recombinant Rabbit Anti-VCL Antibody (clone R09-1F3) | WB, IHC-P | Rabbit IgG |
| VS13-YC1213 | Rabbit Anti-VCL Recombinant Antibody (VS13-YC1213) | WB, IHC-P, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3831 | Rabbit Anti-VCL Recombinant Antibody (clone DS3831AB) | IHC-P | Rabbit IgG |
| MOR-4759 | Rabbit Anti-VCL Recombinant Antibody (clone TH273DS) | WB, IF, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC2455 | PE-A*02:01/Human VCL (GLDVLTAKV) MHC Tetramer | FCM | |
| MHC-LC2456 | PE-A*02:01/Human VCL (RILGAVAKV) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7824 | Anti-VCL Immunohistochemistry Kit | IHC | |
| VS-0525-XY7825 | Anti-Mouse VCL Immunohistochemistry Kit | IHC |
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