PE-A*02:01/Human VCL (RILGAVAKV) MHC Tetramer (CAT#: MHC-LC2456)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human VCL of peptide RILGAVAKV covering 823-831 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • VCL
  • Antigen Species
  • Human
  • Peptide
  • RILGAVAKV
  • Range
  • 823-831
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • VCL; Vinculin; MV; MVCL; CMD1W; CMH15; HEL114

Downloads

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Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3831 Rabbit Anti-VCL Recombinant Antibody (clone DS3831AB) IHC-P Rabbit IgG
MOR-4759 Rabbit Anti-VCL Recombinant Antibody (clone TH273DS) WB, IF, ICC, FC Rabbit IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC2455 PE-A*02:01/Human VCL (GLDVLTAKV) MHC Tetramer FCM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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