Mouse Anti-VDR Recombinant Antibody (VS3-CJ595)
CAT#: VS3-CJ595
This product is a mouse antibody that recognizes human VDR.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47740/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72102/1802_G2_7_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4617/if_selected.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (HBEC3-KT, HDLM-2, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000111424-VDR
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Specifications
- Immunogen
- Purified His-tagged VDR protein (Fragment)
- Host Species
- Mouse
- Type
- Mouse IgA
- Specificity
- Human VDR
- Species Reactivity
- Human
- Applications
- WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Saturated Ammonium Sulfate (SAS)
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.09% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot (1:2000).
Target
- Alternative Names
- NR1I1; PPP1R163
- Gene ID
- 7421
- UniProt ID
- P11473
- Sequence Similarities
- Belongs to the nuclear hormone receptor family. NR1 subfamily.
- Cellular Localization
- Cytoplasm, Nucleus
- Protein Refseq
- NP_000367.1; NP_001017535.1; NP_001017536.1
- Function
- Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (PubMed:28698609, PubMed:16913708, PubMed:15728261, PubMed:10678179).
Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (PubMed:28698609).
The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (PubMed:28698609).
Plays a central role in calcium homeostasis (By similarity).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "VDR"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1719z | Mouse Anti-VDR Recombinant Antibody (clone 37C12) | WB, ELISA, IHC, IP | Mouse IgG2a |
| MRO-1588-CN | Rabbit Anti-VDR Recombinant Antibody (clone JA11-16) | WB, IHC, FC | Rabbit IgG |
| HPAB-1108-CN | Mouse Anti-VDR Recombinant Antibody (HPAB-1108-CN) | ELISA | Mouse IgG |
| ZG-0021U | Rabbit Anti-VDR Recombinant Antibody (clone 3C7) | ELISA, WB, IHC | Rabbit IgG |
| VS3-XY3538 | Rabbit Anti-VDR Recombinant Antibody (clone R04-9B1) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B056(A) | Recombinant Anti-mouse Vdr Intrabody [(D-Arg)9] | PCA, WB, FuncS | scFv-(D-Arg)9 |
| IAB-B056(G) | Recombinant Anti-mouse Vdr Intrabody [+36 GFP] | FACS, ELISA, IF, FuncS | scFv-(+36GFP) |
| IAB-B056(T) | Recombinant Anti-mouse Vdr Intrabody [Tat] | FACS, ICC, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3834 | Rabbit Anti-VDR Recombinant Antibody (clone DS3834AB) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1108-CN-S(P) | Mouse Anti-VDR Recombinant Antibody; scFv Fragment (HPAB-1108-CN-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1108-CN-F(E) | Mouse Anti-VDR Recombinant Antibody; Fab Fragment (HPAB-1108-CN-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7832 | Anti-VDR Immunohistochemistry Kit | IHC | |
| VS-0525-XY7833 | Anti-Mouse VDR Immunohistochemistry Kit | IHC |
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