Mouse Anti-VDR Recombinant Antibody (VS3-CJ595) (CAT#: VS3-CJ595)
This product is a mouse antibody that recognizes human VDR.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47740/if_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47740/if_selected.jpg
Figure 2 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72102/1802_G2_7_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72102/1802_G2_7_selected.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4617/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4617/if_selected.jpg
Figure 4 RNA cell line category: Cell line enhanced (HBEC3-KT, HDLM-2, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000111424-VDR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000111424-VDR
Specifications
- Immunogen
- Purified His-tagged VDR protein (Fragment)
- Host Species
- Mouse
- Type
- Mouse IgA
- Specificity
- Human VDR
- Species Reactivity
- Human
- Applications
- WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Saturated Ammonium Sulfate (SAS)
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.09% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot (1:2000).
Target
- Alternative Names
- NR1I1; PPP1R163
- Gene ID
- 7421
- UniProt ID
- P11473
- Sequence Similarities
- Belongs to the nuclear hormone receptor family. NR1 subfamily.
- Cellular Localization
- Cytoplasm, Nucleus
- Protein Refseq
- NP_000367.1; NP_001017535.1; NP_001017536.1
- Function
- Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (PubMed:28698609, PubMed:16913708, PubMed:15728261, PubMed:10678179).
Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (PubMed:28698609).
The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (PubMed:28698609).
Plays a central role in calcium homeostasis (By similarity).
Recommended Products
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "VDR"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1719z | Mouse Anti-VDR Recombinant Antibody (clone 37C12) | WB, ELISA, IHC, IP | Mouse IgG2a |
| MOB-2221CT | Recombinant Mouse anti-Human VDR Monoclonal antibody (9A7) | ICC/IF, WB | |
| MRO-1588-CN | Rabbit Anti-VDR Recombinant Antibody (clone JA11-16) | WB, IHC, FC | Rabbit IgG |
| MRO-2274-CN | Rabbit Anti-VDR Polyclonal Antibody (MRO-2274-CN) | WB, FC | Rabbit IgG |
| MRO-2275-CN | Rabbit Anti-VDR Polyclonal Antibody (MRO-2275-CN) | WB, IF, FC | Rabbit IgG |
Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B056(A) | Recombinant Anti-mouse Vdr Intrabody [(D-Arg)9] | PCA, WB, FuncS | scFv-(D-Arg)9 |
| IAB-B056(G) | Recombinant Anti-mouse Vdr Intrabody [+36 GFP] | FACS, ELISA, IF, FuncS | scFv-(+36GFP) |
| IAB-B056(T) | Recombinant Anti-mouse Vdr Intrabody [Tat] | FACS, ICC, FuncS | scFv-Tat |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3834 | Rabbit Anti-VDR Recombinant Antibody (clone DS3834AB) | WB, IP | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1108-CN-S(P) | Mouse Anti-VDR Recombinant Antibody; scFv Fragment (HPAB-1108-CN-S(P)) | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1108-CN-F(E) | Mouse Anti-VDR Recombinant Antibody; Fab Fragment (HPAB-1108-CN-F(E)) | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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