Mouse Anti-VEGFC Recombinant Antibody (VS3-CJ994) (CAT#: VS3-CJ994)
This product is a mouse antibody that recognizes human, mouse, and rat VEGFC.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000150630-VEGFC
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000150630-VEGFC
Specifications
- Immunogen
- Recombinant protein of VEGFC
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human, Mouse, Rat VEGFC
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein G affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS, pH 7.3.
- Preservative
- 0.09% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot (1:1000).
Target
- Alternative Names
- VRP; Flt4-L; LMPH1D; LMPHM4
- Gene ID
- 7424
- UniProt ID
- P49767
- Sequence Similarities
- Belongs to the PDGF/VEGF growth factor family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3, but only the fully processed form could activate VEGFR-2. VEGF-C first form an antiparallel homodimer linked by disulfide bonds. Before secretion, a cleavage occurs between Arg-227 and Ser-228 producing a heterotetramer. The next extracellular step of the processing removes the N-terminal propeptide. Finally the mature VEGF-C is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions.
- Protein Refseq
- NP_005420.1
- Function
- Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates KDR/VEGFR2 and FLT4/VEGFR3 receptors.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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IgG Antibody Products
Human Antibody Products
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Mouse Antibody Products
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1722z | Mouse Anti-VEGFC Recombinant Antibody (clone 10F5) | WB, ICC, IF, IHC | Mouse IgG2a |
| MOB-2183MZ | Recombinant Mouse Anti-Human VEGFC Antibody (clone 0/F8) | IHC-Fr, WB | Mouse antibody |
| MRO-2271-CN | Rabbit Anti-VEGFC Polyclonal Antibody (MRO-2271-CN) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-QX1233 | Mouse Anti-VEGFC Recombinant Antibody (clone 2E2-F8-C6) | WB | |
| VS-0224-XY139 | Mouse Anti-VEGFC Recombinant Antibody (VS-0224-XY139) | ELISA, WB, FC, IF, IP, IHC | Mouse IgG2a, kappa |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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