Mouse Anti-VEGFC Recombinant Antibody (VS3-CJ994)
CAT#: VS3-CJ994
This product is a mouse antibody that recognizes human, mouse, and rat VEGFC.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced.
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000150630-VEGFC
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Specifications
- Immunogen
- Recombinant protein of VEGFC
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human, Mouse, Rat VEGFC
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein G affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS, pH 7.3.
- Preservative
- 0.09% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot (1:1000).
Target
- Alternative Names
- VRP; Flt4-L; LMPH1D; LMPHM4
- Gene ID
- 7424
- UniProt ID
- P49767
- Sequence Similarities
- Belongs to the PDGF/VEGF growth factor family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3, but only the fully processed form could activate VEGFR-2. VEGF-C first form an antiparallel homodimer linked by disulfide bonds. Before secretion, a cleavage occurs between Arg-227 and Ser-228 producing a heterotetramer. The next extracellular step of the processing removes the N-terminal propeptide. Finally the mature VEGF-C is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions.
- Protein Refseq
- NP_005420.1
- Function
- Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates KDR/VEGFR2 and FLT4/VEGFR3 receptors.
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Related Signaling Pathways
TNF Signaling Pathway
Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "VEGFC"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1722z | Mouse Anti-VEGFC Recombinant Antibody (clone 10F5) | WB, ICC, IF, IHC | Mouse IgG2a |
| MOB-0226MC | Anti-Human VEGF-C Antibody | WB, ICC, IF, IHC, IHC-P | |
| MRO-2271-CN | Rabbit Anti-VEGFC Polyclonal Antibody (MRO-2271-CN) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-QX1233 | Mouse Anti-VEGFC Recombinant Antibody (clone 2E2-F8-C6) | WB | |
| VS-0224-XY139 | Mouse Anti-VEGFC Recombinant Antibody (VS-0224-XY139) | ELISA, WB, FC, IF, IP, IHC | Mouse IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-661CL | Human Anti-VEGFC Recombinant Antibody (TAB-661CL) | ELISA | Human IgG |
| TAB-311CQ | Human Anti-VEGFC Recombinant Antibody (TAB-311CQ) | ELISA, WB | Human IgG |
| TAB-311CQ-S(P) | Human Anti-VEGFC Recombinant Antibody (TAB-311CQ-S(P)); scFv Fragment | ELISA, WB, Neut | Human scFv |
| TAB-311CQ-F(E) | Human Anti-VEGFC Recombinant Antibody (TAB-311CQ-F(E)); Fab Fragment | ELISA, WB, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-309CQ | Human Anti-VEGFC Recombinant Antibody (TAB-309CQ) | Block, ELISA, FuncS | Humanized antibody |
| TAB-309CQ-S(P) | Human Anti-VEGFC Recombinant Antibody; scFv Fragment (TAB-309CQ-S(P)) | ELISA, FC, WB, BL | Humanized scFv |
| TAB-309CQ-F(E) | Human Anti-VEGFC Recombinant Antibody; Fab Fragment (TAB-309CQ-F(E)) | ELISA, FC, WB, BL | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-310CQ | Mouse Anti-VEGFC Recombinant Antibody (TAB-310CQ) | Block, ELISA, FuncS | Mouse IgG2a, κ |
| TAB-310CQ-S(P) | Mouse Anti-VEGFC Recombinant Antibody; scFv Fragment (TAB-310CQ-S(P)) | ELISA, FC, WB, BL | Mouse scFv |
| TAB-310CQ-F(E) | Mouse Anti-VEGFC Recombinant Antibody; Fab Fragment (TAB-310CQ-F(E)) | ELISA, FC, WB, BL | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2468 | Anti-VEGFC Immunohistochemistry Kit | IHC | |
| VS-0525-XY7842 | Anti-Mouse VEGFC Immunohistochemistry Kit | IHC | |
| VS-0525-XY7841 | Anti-Human VEGFC Immunohistochemistry Kit | IHC |
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