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Anti-VEGFC Recombinant Antibody Products

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Anti-VEGFC Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs is a world leader in the creation of recombinant antibodies and is pleased to provide a high-end selection of anti-VEGFC recombinant antibody products. Engineered with unparalleled precision and validated for superior performance, these antibodies empower researchers worldwide to advance their studies in angiogenesis, lymphangiogenesis, and related therapeutic areas, ensuring reliable and reproducible results for critical discoveries.

VEGFC: A Key Target for Angiogenesis and Lymphangiogenesis Therapies

Vascular Endothelial Growth Factor-C (VEGFC) is a pivotal member of the VEGF family, primarily known for its crucial roles in lymphangiogenesis and angiogenesis. It triggers signaling pathways essential for vascular growth and permeability by acting as a ligand for VEGF receptor-2 (VEGFR-2) and VEGF receptor-3 (VEGFR-3). Extensive research highlights VEGFC's involvement in various physiological and pathological processes, making it a significant target for developing treatments for diseases associated with abnormal vascular and lymphatic growth, such as cancer and lymphedema.

Alternative Names

Vascular endothelial growth factor C; VEGF-C; Flt4-L; LMPH1D; VRP; LMPHM4.

Background

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors.

Protein class

Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, RAS pathway related proteins, Transporters

Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Adipocytes, Microglial cells, Endothelial cells, Leydig cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced

Interaction

Homodimer; non-covalent and antiparallel (PubMed:20145116). Interacts with FLT4/VEGFR3; the interaction is required for FLT4/VEGFR3 homodimarization and activation (PubMed:23878260).

Molecular function

Developmental protein, Growth factor, Mitogen

More Types Infomation

Anti-VEGFC rAb Products

Our anti-VEGFC recombinant antibody solutions are meticulously developed to provide great specificity and affinity, providing researchers with extremely dependable tools. Leveraging modern recombinant technology, these antibodies provide lot-to-lot uniformity and minimum batch variation, which is crucial for reliable experimental results. Their excellent purity and verified performance make them perfect for a variety of applications, such as ELISA, Western Blot, Immunohistochemistry, and Flow Cytometry, allowing you to accelerate your study confidently.

Cat. No. Product Name Target Species Host Species Applications
MOB-1722z Mouse Anti-VEGFC Recombinant Antibody (clone 10F5) Human Mouse IgG2a WB, ICC, IF, IHC
TAB-661CL Human Anti-VEGFC Recombinant Antibody (TAB-661CL) Human Human IgG ELISA
VS3-QX1233 Mouse Anti-VEGFC Recombinant Antibody (clone 2E2-F8-C6) Human, Mouse, Rat Mouse WB
MOB-2183MZ Recombinant Mouse Anti-Human VEGFC Antibody (clone 0/F8) Human Mouse antibody IHC-Fr, WB
MRO-2271-CN Rabbit Anti-VEGFC Polyclonal Antibody (MRO-2271-CN) Human Rabbit IgG WB, IF, IHC, FC

Table 1. Featured anti-VEGFC recombinant antibody products at Creative Biolabs.

Creative Quality Control

Creative Biolabs prioritizes thorough quality control for our anti-VEGFC recombinant antibody products. Each batch is rigorously validated using extensive biochemical and functional tests, such as binding affinity measurements, specificity testing, and application-specific performance verification. This careful procedure ensures that our antibodies are of the greatest purity, have constant activity, and work well, meeting both industry standards and your research demands.

Customer Reviews

Excellent
El***t
Recombinant Mouse Anti-Human VEGFC Antibody (clone 0/F8) (MOB-2183MZ)
The anti-VEGFC recombinant antibody from Creative Biolabs has improved our angiogenesis investigations. Its excellent specificity and minimal background noise greatly improved our IHC findings, saving us time and resources. We've continuously produced clear and accurate data, which is critical for our continued therapeutic development.
15/Jun/2024
Excellent
Al***n
Mouse Anti-VEGFC Recombinant Antibody (TAB-310CQ) (TAB-310CQ)
We carried out Creative Biolabs' anti-VEGFC antibody in preclinical animals and obtained remarkable results. The antibody's constant effectiveness across several experiments has contributed greatly to our understanding of lymphatic vessel remodeling in tumor microenvironments. Their product stands out due to its durability and brilliance.
11/Sep/2024
Excellent
Ch***g
Mouse Anti-VEGFC Recombinant Antibody (VS-0224-XY139) (VS-0224-XY139)
Our research was a success because of Creative Biolabs' technical help and the remarkable performance of their anti-VEGFC recombinant antibody. The antibody provided accurate and reproducible findings in our flow cytometry studies, which were critical for our cell-based study. We strongly suggest their goods for any challenging research applications.
22/Jan/2025

rAb Production

Our anti-VEGFC recombinant antibody products are created utilizing cutting-edge mammalian expression techniques, resulting in optimum post-translational modifications and biological activity. This state-of-the-art production facility guarantees high-yield, high-purity antibodies free of contaminants. Every step, from gene synthesis to purification, follows tight protocols, resulting in a product that provides reliable and excellent performance for your most crucial tests.

Featured Anti-VEGFC Recombinant Antibody Production PlatformsMilligram-scale. (Creative Biolabs Original)
Fig.1 Milligram-scale anti-VEGFC recombinant antibody production.

Gram-scale. (Creative Biolabs Original)Fig.2 Gram-scale anti-VEGFC recombinant antibody production.

rAb Modalities

Anti-VEGFC recombinant antibodies from Creative Biolabs are available in a range of modalities, including origins in mammals, isotypes, and conjugation methods, giving researchers flexibility for a wide range of research applications.

VEGFC antibody production and modalities. (Creative Biolabs Original)Fig.3 Full-length anti-VEGFC recombinant antibody production and modalities.

VEGFC-Targeted Drug Information

Company Research phase Classification Condition
4D Molecular Therapeutics (Originator) Phase II Adeno-Associated Viral (AAV) Vectors
DNA-Directed RNA Interference (ddRNAi)
MicroRNA
Diabetic macular edema
Wet macular degeneration (exudative)
Innovent Biologics (Originator) Phase I Bispecific Antibody Fusions
Fc Fusion Proteins
Polypeptides, from 41 AA
Single-Chain V-Domain Antibody Fragment (scFv)
Wet macular degeneration (exudative)
RevOpsis Therapeutics (Originator) Preclinical Trispecific Antibodies Wet macular degeneration (exudative)
National Cerebral Cardiovascular Center Preclinical Oligoribonucleotide (RNA)
Short Hairpin RNA (shRNA)
Cancer, breast, metastatic
Innovent Biologics (Originator) Biological Testing Bispecific Antibody Fusions
Cancer Immunotherapy
Fc Fusion Proteins
Polypeptides, from 41 AA
Single-Domain Antibodies
Cancer
Eye Disorders
Chengdu Yuanpu Biotechnology (Originator) Biological Testing Cancer Immunotherapy
Fc Fusion Proteins
Polypeptides, from 41 AA
Age-related macular degeneration (AMD)
Chengdu Yuanpu Biotechnology (Originator) Biological Testing Cancer Immunotherapy
Fc Fusion Proteins
Polypeptides, from 41 AA
Age-related macular degeneration (AMD)
CNRS (Originator)
INSERM (Originator)
Universite Cote d'Azur (UCA) (Originator)
Biological Testing Cancer Immunotherapy
Humanized Monoclonal Antibodies
Cancer
CNRS (Originator)
INSERM (Originator)
Universite Cote d'Azur (UCA) (Originator)
Biological Testing Cancer Immunotherapy
Chimeric Monoclonal Antibodies
Cancer
GeneScience Pharmaceuticals (Originator) Biological Testing Bispecific Antibody Fusions
Cancer Immunotherapy
Fusion Proteins
Human Monoclonal Antibodies
Polypeptides, from 41 AA
Cancer
Changzhou University (Originator) Biological Testing Oligoribonucleotide (RNA)
Short Hairpin RNA (shRNA)
Cancer, endometrium (adenocarcinoma)
Juseong College Ind. Acad. Coop. (Originator) Biological Testing Adeno-Associated Viral (AAV) Vectors
Gene Therapy
Cancer

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Table 2. Public drug targeting VEGFC.

Creative Biolabs is committed to advancing scientific discovery with our cutting-edge anti-VEGFC recombinant antibody products. We encourage you to browse our extensive inventory and learn how our high-quality reagents may help you further your study. Please contact us directly if you need extensive product information, technical help, or to discuss bespoke requirements.

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