Rabbit Anti-WNT2 Recombinant Antibody (clone R01-5I9) (CAT#: VS3-XY3541)

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human, Mouse and Rat WNT2

• Species Reactivity
• Human, Mouse, Rat

• Clone
• R01-5I9

• Applications
• WB

• Related Disease
• Colorectal Cancer; Frontotemporal Dementia

• Clonality
• Monoclonal

• Aggregation
• < 5%

• Format
• Liquid

• Buffer
• PBS (pH 7.4), 150 mM NaCl and 50% glycerol

• Preservative
• 0.02% sodium azide

• Storage
• Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Shipping
• Ice packs

• Application Notes
• WB: 1/500-1/1000

• Alternative Names
• IRP; INT1L1

• Gene ID
• 7472

• UniProt ID
• P09544

• Long Name
• Wnt family member 2

• Cellular Localization
• Secreted

• Post Translation Modifications
• Glycosylation at Asn295 (NX_P09544 [NX_P09544-1])
  Modification sites at PhosphoSitePlus (P09544)
  Glycosylation from GlyGen (P09544) 1 site

• Protein Refseq
• NP_003382.1

• Function
• Ligand for members of the frizzled family of seven transmembrane receptors.
  Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:20018874).
  Functions as upstream regulator of FGF10 expression.
  Plays an important role in embryonic lung development.

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS

Secondary Antibody

• 2RD-A1473-YJ
• Goat Anti-Rabbit IgG-F(ab')2 Secondary antibody