Mouse Anti-WNT4 Recombinant Antibody (VS3-CJ1055) (CAT#: VS3-CJ1055)

• Immunogen
• Recombinant protein between 30-351 amino acids from human WNT4

• Host Species
• Mouse

• Type
• Mouse IgG1, κ

• Specificity
• Human, Mouse WNT4

• Species Reactivity
• Human, Mouse

• Applications
• WB

• Conjugate
• Unconjugated

• Purification
• Affinity purified

• Purity
• >95% as determined by SDS-PAGE

• Format
• Liquid

• Buffer
• PBS

• Preservative
• 0.09% Sodium Azide

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• This antibody has been tested for use in Western Blot (1:4000).

• Alternative Names
• WNT-4; SERKAL

• Gene ID
• 54361

• UniProt ID
• P56705

• Sequence Similarities
• Belongs to the Wnt family.

• Cellular Localization
• Extracellular matrix, Secreted

• Post Translation Modifications
• Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.

• Protein Refseq
• NP_110388.2

• Function
• Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in the embryonic development of the urogenital tract and the lung (PubMed:15317892, PubMed:16959810, PubMed:18179883, PubMed:18182450).
  Required for normal mesenchyme to epithelium transition during embryonic kidney development. Required for the formation of early epithelial renal vesicles during kidney development (By similarity).
  Required for normal formation of the Mullerian duct in females, and normal levels of oocytes in the ovaries (PubMed:15317892, PubMed:16959810, PubMed:18182450).
  Required for normal down-regulation of 3 beta-hydroxysteroid dehydrogenase in the ovary (PubMed:15317892, PubMed:16959810, PubMed:18182450).
  Required for normal lung development and for normal patterning of trachael cartilage rings (By similarity).

Secondary Antibody

• 2RD-A1460-YJ
• Goat Anti-Mouse IgG1 Secondary antibody

• 2RD-A1562-YJ
• Rabbit Anti-Mouse IgG1 Secondary antibody (Clone RM106)

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS