Mouse Anti-WNT4 Recombinant Antibody (VS3-CJ1055)
CAT#: VS3-CJ1055
This product is a mouse antibody that recognizes human, and mouse WNT4.
Specifications
- Immunogen
- Recombinant protein between 30-351 amino acids from human WNT4
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human, Mouse WNT4
- Species Reactivity
- Human, Mouse
- Applications
- WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.09% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot (1:4000).
Target
- Alternative Names
- WNT-4; SERKAL
- Gene ID
- 54361
- UniProt ID
- P56705
- Sequence Similarities
- Belongs to the Wnt family.
- Cellular Localization
- Extracellular matrix, Secreted
- Post Translation Modifications
- Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
- Protein Refseq
- NP_110388.2
- Function
- Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in the embryonic development of the urogenital tract and the lung (PubMed:15317892, PubMed:16959810, PubMed:18179883, PubMed:18182450).
Required for normal mesenchyme to epithelium transition during embryonic kidney development. Required for the formation of early epithelial renal vesicles during kidney development (By similarity).
Required for normal formation of the Mullerian duct in females, and normal levels of oocytes in the ovaries (PubMed:15317892, PubMed:16959810, PubMed:18182450).
Required for normal down-regulation of 3 beta-hydroxysteroid dehydrogenase in the ovary (PubMed:15317892, PubMed:16959810, PubMed:18182450).
Required for normal lung development and for normal patterning of trachael cartilage rings (By similarity).
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Related Signaling Pathways
Canonical Wnt Signaling Pathway
mTOR Signaling Pathway
Non-Canonical Wnt Signaling Pathway
Related Diseases
Endometrial Cancer
Throid Cancer
Cushing Syndrome
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "WNT4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4760 | Rabbit Anti-WNT4 Recombinant Antibody (clone TH274DS) | WB, IF, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY1598 | Mouse Anti-WNT4 Recombinant Antibody (clone 4G1) | WB, IP, IF | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7931 | Anti-WNT4 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7932 | Anti-Mouse WNT4 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7933 | Anti-Human WNT4 Immunohistochemistry Kit | IHC |
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