Rabbit Anti-WTAP Recombinant Antibody (VS3-FY2919) (CAT#: VS3-FY2919)
The rabbit anti-WTAP recombinant monoclonal antibody has high affinity for human WTAP protein. This monoclonal antibody proves valuable in disease research related to Wilms Tumor 5 and Wilms Tumor 1. The optimal dilution for this antibody is Immunoprecipitation (1/20), Western Blot (1/500-1/1000), Immunohistochemistry (1/50-1/100).
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human WTAP
- Species Reactivity
- Human
- Applications
- Western Blot, Immunohistochemistry, Immunoprecipitation
- Conjugate
- Unconjugated, FITC
- Related Disease
- Wilms Tumor 5 and Wilms Tumor 1
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunoprecipitation: 1/20
Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Target
- Alternative Names
- WT1 Associated Protein; Wilms Tumor 1-Associating Protein; Wilms Tumor 1 Associated Protein; Female-Lethal(2)D Homolog; HFL(2)D; Putative Pre-MRNA Splicing Regulator Female-Lethal(2D); Wilms Tumour 1-Associating Protein
- Gene ID
- 9589
- UniProt ID
- Q15007
- Sequence Similarities
- Belongs to the fl(2)d family.
- Cellular Localization
- Nucleus speckle
Nucleus, nucleoplasm
Cytoplasm
- Post Translation Modifications
- Ubiquitination at Lys83 and Lys98 (NX_Q15007 [NX_Q15007-1])
Modification sites at PhosphoSitePlus (Q15007)
Glycosylation from GlyGen (Q15007) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_016867004.1; XP_016867005.1; XP_047275534.1; XP_054212833.1
- Function
- Acts as a mRNA splicing regulator (PubMed:12444081).
Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed:17088532).
Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "WTAP"
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0631MZ | Chicken Anti-WTAP Polyclonal IgY | WB | Chicken antibody |
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For Research Use Only. Not For Clinical Use.
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