AbPlus™ Anti-YAP1 Magnetic Beads (CBACN-585) (CAT#: VS-0424-XY277)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-YAP1 specific antibody (CBACN-585)

• Target
• YAP1

• Immunogen
• Human YAP1 (aa 350-450)

• Target Species
• Human

• Antibody Clone
• CBACN-585

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

• Alternative Names
• Yes Associated Protein 1; Yes-Associated Protein YAP65 Homolog; Yes-Associated Protein 1; Protein Yorkie Homolog; YAP65; Transcriptional Coactivator YAP1; Yes-Associated Protein 1, 65kDa; 5 KDa Yes-Associated Protein

• Gene ID
• 10413

• UniProt ID
• P46937

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