Rabbit Anti-YES1 Recombinant Antibody (clone R07-8B3)
CAT#: VS3-FY1940
This anti-Yes1 antibody detected positive in western blot analysis of Yes1 in K562 lysates. The recombinant monoclonal antibody with high affinity in targeting human YES1. It is suitable for use in a variety of assays, including WB, IP. This R07-8B3 antibody is validated for western blot analysis of yes1 in K562 lysates.
Tested Data
WB
Figure 1 Anti-YES1 Antibody (VS3-FY1940) in WB.
The Yes1 expression in K562 lysates were detected using the anti-Yes1 by western blot assay.
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Specifications
- Immunogen
- Synthetic peptide of human Yes1
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human YES1
- Species Reactivity
- Human
- Clone
- R07-8B3
- Applications
- Western Blot, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 61 kDa, while the observed molecular weight stands at 61 kDa.
- Related Disease
- Sarcoma and Colorectal Cancer
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunoprecipitation: 1/20
Target
- Alternative Names
- YES Proto-Oncogene 1, Src Family Tyrosine Kinase; V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1; Proto-Oncogene C-Yes; EC 2.7.10.2; P61-YES; Yes; YES1 Proto-Oncogene, Src Family Tyrosine Kinase; Proto-Oncogene Tyrosine-Protein Kinase YES
- Gene ID
- 7525
- UniProt ID
- P07947
- Sequence Similarities
- Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
- Cellular Localization
- Cell membrane, Cytoplasm, Cytoskeleton, Membrane
- Post Translation Modifications
- Phosphorylation by CSK on the C-terminal tail maintains the enzyme in an inactive state.
Autophosphorylation at Tyr-426 maintains enzyme activity by blocking CSK-mediated inhibition.
(P07947-YES_HUMAN)
Palmitoylation at Cys-3 promotes membrane localization. (P07947-YES_HUMAN)
Ubiquitination at Lys235 (NX_P07947 [NX_P07947-1])
Modification sites at PhosphoSitePlus (P07947)
Glycosylation from GlyGen (P07947) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_005258196.1; XP_016881449.1; XP_024307011.1; XP_024307012.1; XP_024307013.1
- Function
- Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGFR, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "YES1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3691z | Mouse Anti-YES1 Recombinant Antibody (clone 22A8) | WB, ELISA | Mouse IgG1 |
| ZG-0451F | Mouse Anti-YES1 Recombinant Antibody (ZG-0451F) | WB, ELISA | Mouse IgG |
| VS3-CJ477 | Mouse Anti-YES1 Recombinant Antibody (VS3-CJ477) | WB | Mouse IgG |
| VS3-XY1612 | Mouse Anti-YES1 Recombinant Antibody (clone 2F3E6) | ELISA, WB | Mouse IgG1 |
| VS3-FY2923 | Mouse Anti-YES1 Recombinant Antibody (VS3-FY2923) | WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3903 | Rabbit Anti-YES1 Recombinant Antibody (clone DS3903AB) | WB, IHC, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC376 | AbPlus™ Anti-YES1 Magnetic Beads (VS-0724-YC376) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2505 | Anti-YES1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7982 | Anti-Mouse YES1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7981 | Anti-Human YES1 Immunohistochemistry Kit | IHC |
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