Mouse Anti-YES1 Recombinant Antibody (VS3-FY2923)
CAT#: VS3-FY2923
The anti-YES1 product is a mouse recombinant monoclonal antibody. It has been specifically designed to target the human YES1 protein. It cross-reacts with mouse, rat species. The calculated molecular weight of the protein is about 60.8 kDa. The monoclonal antibody can be used in the area of Sarcoma and Colorectal Cancer. This monoclonal antibody is suitable for employment in Western Blot (1/500-1/2000).
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human, Mouse and Rat YES1
- Species Reactivity
- Human, Mouse, Rat
- Applications
- Western Blot
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 60.8 kDa.
- Related Disease
- Sarcoma and Colorectal Cancer
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Target
- Alternative Names
- YES Proto-Oncogene 1, Src Family Tyrosine Kinase; V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1; Proto-Oncogene C-Yes; EC 2.7.10.2; P61-YES; Yes; YES1 Proto-Oncogene, Src Family Tyrosine Kinase; Proto-Oncogene Tyrosine-Protein Kinase YES
- Gene ID
- 7525
- UniProt ID
- P07947
- Sequence Similarities
- Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
- Cellular Localization
- Cell membrane, Cytoplasm, Cytoskeleton, Membrane
- Post Translation Modifications
- Phosphorylation by CSK on the C-terminal tail maintains the enzyme in an inactive state.
Autophosphorylation at Tyr-426 maintains enzyme activity by blocking CSK-mediated inhibition.
Palmitoylation at Cys-3 promotes membrane localization. (P07947-YES_HUMAN)
Ubiquitination at Lys235 (NX_P07947 [NX_P07947-1])
Modification sites at PhosphoSitePlus (P07947)
Glycosylation from GlyGen (P07947) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_005258196.1; XP_016881449.1; XP_024307011.1; XP_024307012.1; XP_024307013.1
- Function
- Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGFR, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "YES1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3903 | Rabbit Anti-YES1 Recombinant Antibody (clone DS3903AB) | WB, IHC, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0451F | Mouse Anti-YES1 Recombinant Antibody (ZG-0451F) | WB, ELISA | Mouse IgG |
| VS3-CJ477 | Mouse Anti-YES1 Recombinant Antibody (VS3-CJ477) | WB | Mouse IgG |
| VS3-XY1612 | Mouse Anti-YES1 Recombinant Antibody (clone 2F3E6) | ELISA, WB | Mouse IgG1 |
| VS3-FY1940 | Rabbit Anti-YES1 Recombinant Antibody (clone R07-8B3) | WB, IP | Rabbit IgG |
| VS13-YC1234 | Rabbit Anti-YES1 Recombinant Antibody (VS13-YC1234) | WB, IHC-P, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC376 | AbPlus™ Anti-YES1 Magnetic Beads (VS-0724-YC376) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2505 | Anti-YES1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7982 | Anti-Mouse YES1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7981 | Anti-Human YES1 Immunohistochemistry Kit | IHC |
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