Recombinant Anti-ZIKV E (Domain II x Domain III) Biparatopic Antibody, Tandem scFv (Clone SMZAb2 x Clone SMZAb1)

CAT#: VS-0525-YC195

Recombinant Anti-ZIKV E (Domain II x Domain III) Biparatopic Antibody, Tandem scFv (Clone SMZAb2 x Clone SMZAb1) is a biparatopic antibody (bpAb) that targets two distinct epitopes on the ZIKV E protein. This construct was designed as a tandem scFv. It consists of the SMZAb2 scFv (binding domain II) N-terminally fused to the SMZAb1 scFv (specific for domain III of ZIKV E protein).

Specifications

  • Host Animal 1
  • Human
  • Host Animal 2
  • Human
  • Specificity
  • ZIKV E protein
  • Species Reactivity
  • ZIKV
  • Type
  • Tandem scFv
  • Valency
  • 1 + 1
  • Clone 1
  • SMZAb2
  • Clone 2
  • SMZAb1
  • Epitope 1
  • Domain II
  • Epitope 2
  • Domain III
  • Purity
  • >90%
  • Purification
  • Affinity purified
  • Applications
  • ELISA, Neut
  • Concentration
  • Lot specific
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
  • Long Name
  • Zika virus (ZIKV) Envelope protein

Target

  • Introduction
  • Zika virus (ZIKV) infection causes devastating congenital abnormities and Guillain-Barré syndrome. The ZIKV envelope (E) protein is responsible for viral entry and represents a major determinant for viral pathogenesis. Like other flaviviruses, the ZIKV E protein is glycosylated at amino acid N154.
  • Alternative Names
  • Zika virus structural protein E; ZIKV E
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VS-0625-XY195 Human Anti-ZIKV E Vaccinal Antibody (VS-0625-XY195) ELISA, FC, Neut Human IgG
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