Recombinant Human Anti-ZIKV E Antibody (C10)
CAT#: PABC-264
This product is a recombinant Human antibody that can recognize ZIKV E. At pH6.5, antibody C10 locks all virus surface E proteins, and at pH5.0, it locks the E protein raft structure.
Published Data
Neut
Figure 1 Binding characteristics of used mAbs. Characteristics of the mAbs used for dimer assembly.
Several mouse or human (M/H) derived mAbs were used for sRecE dimer assembly, indicating their DENV and ZIKV binding potential. Flavivirus cross reactive (F-CR), weakly, medium or strong (W/M/S) neutralizing, E-domain I, II, III (DI, DII, DIII), fusion loop (FL), quaternary epitope (Q).
Metz, S. W., Gallichotte, E. N., Brackbill, A., Premkumar, L., Miley, M. J., Baric, R., & de Silva, A. M. (2017). In vitro assembly and stabilization of dengue and Zika virus envelope protein homo-dimers. Scientific reports, 7(1), 4524.
FuncS
Figure 2 Antibody mediated dimer assembly.
Indicated amounts of DENV and ZIKV sRecE were incubated with 500 ng of C10 mAb in solution. Protein/mAb complexes were loaded on Ni²⁺-coated plates and captured antibodies were detected.
Metz, S. W., Gallichotte, E. N., Brackbill, A., Premkumar, L., Miley, M. J., Baric, R., & de Silva, A. M. (2017). In vitro assembly and stabilization of dengue and Zika virus envelope protein homo-dimers. Scientific reports, 7(1), 4524.
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Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- ZIKV E
- Species Reactivity
- ZIKV
- Clone
- C10
- Applications
- ELISA, Neut, FuncS
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- The antibody C10 has been reported in applications of Enzyme-linked Immunosorbent Assay, Neutralization, Functional Assay. It's recommended that the optimal antibody concentration, dilution, incubition time etc. be carefully titrated in specific assays.
Target
- Alternative Names
- Zika virus structural protein E; ZIKV E
- UniProt ID
- A0A024B7W1
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "Clone C10"
- CAT
- Product Name
See other products for "ZIKV E"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-264 | Recombinant Human Anti-ZIKV E Antibody Fab Fragment (C10) | ELISA, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-264 | Recombinant Human Anti-ZIKV E Antibody scFv Fragment (C10) | ELISA, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1765CQ | Human Anti-ZIKV E Recombinant Antibody (clone SMZAb5) | Neut, FuncS, ELISA | Human IgG1 |
| VS-0323-CJ67 | Chicken Anti-ZIKV E Recombinant Antibody (clone ZIKVEF2L01) | ELISA, WB | Chicken IgY |
| VS-0323-CJ68 | Chicken Anti-ZIKV E Recombinant Antibody (clone ZIKVEF3S06) | ELISA, WB | Chicken IgY |
| VS-0323-CJ69 | Chicken Anti-ZIKV E Recombinant Antibody (clone ZIKVEF3S07) | ELISA, WB | Chicken IgY |
| VS-0323-CJ70 | Chicken Anti-ZIKV E Recombinant Antibody (clone ZIKVEF3S13) | ELISA, WB | Chicken IgY |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC195 | Recombinant Anti-ZIKV E (Domain II x Domain III) Biparatopic Antibody, Tandem scFv (Clone SMZAb2 x Clone SMZAb1) | ELISA, Neut | Tandem scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-XY195 | Human Anti-ZIKV E Vaccinal Antibody (VS-0625-XY195) | ELISA, FC, Neut | Human IgG |
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