Human Anti-ZIKV E Recombinant Antibody (clone SMZAb5) (CAT#: FAMAB-1765CQ)
This product is a recombinant human antibody that recognizes ZIKV E. The antibody was purified by affinity chromatography. It can be used in Neut, FuncS, ELISA.
Specific Inquiry
Neut
Figure 1 The plasmablast-derived human nmAbs SMZAb1, SMZAb2, and SMZAb5 neutralize ZIKV in vitro.
Ninety-one mAbs generated from a ZIKV-infected patient were screened for ZIKV-neutralization potency using Vero cell infectivity assays, and the three most potent-SMZAb1, SMZAb2, and SMZAb5, neutralized ZIKV at low concentrations. The neutralization titers were determined by focus reduction neutralization test (FRNT).
Magnani, D. M., Rogers, T. F., Beutler, N., Ricciardi, M. J., Bailey, V. K., Gonzalez-Nieto, L., ... & Watkins, D. I. (2017). Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques. Science translational medicine, 9(410), eaan8184.
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- ZIKV E protein
- Species Reactivity
- ZIKV
- Clone
- SMZAb5
- Applications
- Neut, FuncS, ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Zika virus structural protein E; ZIKV E
- UniProt ID
- Q91KX7
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone SMZAb5"
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-264 | Recombinant Human Anti-ZIKV E Antibody (C10) | ELISA, Neut, FuncS | Human IgG |
| FAMAB-1560CQ | Human Anti-ZIKV E Recombinant Antibody (clone A9E) | Neut, WB, ELISA | Human IgG1 |
| VS-0323-CJ67 | Chicken Anti-ZIKV E Recombinant Antibody (clone ZIKVEF2L01) | ELISA, WB | Chicken IgY |
| VS-0323-CJ68 | Chicken Anti-ZIKV E Recombinant Antibody (clone ZIKVEF3S06) | ELISA, WB | Chicken IgY |
| VS-0323-CJ69 | Chicken Anti-ZIKV E Recombinant Antibody (clone ZIKVEF3S07) | ELISA, WB | Chicken IgY |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-264 | Recombinant Human Anti-ZIKV E Antibody Fab Fragment (C10) | ELISA, Neut | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-264 | Recombinant Human Anti-ZIKV E Antibody scFv Fragment (C10) | ELISA, Neut | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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