Human Anti-ZIKV E Vaccinal Antibody (VS-0625-XY195)

CAT#: VS-0625-XY195

This vaccinal antibody targets ZIKV E and is applicable for ELISA, FC and Neut. With Fc segment engineering, it induces vaccine-like effects and enhances antiviral efficacy by improving antibody-dependent cellular cytotoxicity and phagocytosis.

Specifications

  • Target
  • ZIKV E
  • Host Animal
  • Human
  • Applications
  • ELISA; FC; Neut
  • Specificity
  • ZIKV E
  • Species Reactivity
  • ZIKV
  • Type
  • Human IgG
  • Purity
  • >95%, determined by SDS-PAGE
  • Purification
  • Protein A purified
  • Epitope
  • It binds to both E protomers forming dimers within one icosahedral asymmetric unit
  • Format
  • Liquid
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Target

  • Introduction
  • Zika virus (ZIKV) is one of several medically important flaviviruses transmitted by mosquitos to humans. Flaviviruses are positive-sense RNA viruses of approximately 50 nm in diameter with a lipid bilayer containing the envelope (E) and premembrane/membrane (prM/M) glycoproteins. The ectodomain of E protein is composed of two non-continuous domains (EDI and EDII) and a continuous immunoglobulin-like domain (EDIII). The flavivirus E glycoprotein, essential for viral attachment and entry into host cells, is a major target of human antibodies.
  • Related Disease
  • Severe neurological diseases
  • Alternative Names
  • Zika virus envelope protein
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COA

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Secondary Antibody

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PFBC-264 Recombinant Human Anti-ZIKV E Antibody Fab Fragment (C10) ELISA, Neut Human Fab
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PSBC-264 Recombinant Human Anti-ZIKV E Antibody scFv Fragment (C10) ELISA, Neut Human scFv
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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