APC-DRB1*04:05/Human CEA (LWWVNNQSLPVSP) MHC Tetramer
CAT#: MHC-YF1026
This product is a MHC tetramer of biotinylated peptide/MHC complex composed CEA-derived peptide of LWWVNNQSLPVSP sequence covering 321-333 and DRB1*04:05 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specifications
- Allele
- DRB1*04:05
- Class
- Class II
- MHC Species
- Human
- Antigen
- CEA
- Antigen Species
- Human
- Peptide
- LWWVNNQSLPVSP
- Range
- 321-333
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
- Alternative Names
- CEA; CD66e
- Gene ID
- 1048
- UniProt ID
- P06731
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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|---|---|---|---|
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|---|---|---|---|
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