Recombinant mouse monoclonal antibody specially binds to human CEA. This anti-human CEA antibody C1 can be potential therapeutic use in cancers types known to express CEA.
Figure 1 Anti-CEA antibody responses by ELISA.
The arrows indicate doses of rV-CEA at zero time and 8 weeks.
Conry, R. M., Allen, K. O., Lee, S. W., Moore, S. E., Shaw, D. R., & LoBuglio, A. F. (2000). Human autoantibodies to carcinoembryonic antigen (CEA) induced by a vaccinia-CEA vaccine. Clinical cancer research, 6(1), 34-41.
Figure 2 Western immunoblot with baculovirus rCEA protein using sera from two patients immunized with rV-CEA.
The arrow indicates a band at approximately Mr 120,000 produced by the COL-1 anti-CEA antibody as a positive control.
Conry, R. M., Allen, K. O., Lee, S. W., Moore, S. E., Shaw, D. R., & LoBuglio, A. F. (2000). Human autoantibodies to carcinoembryonic antigen (CEA) induced by a vaccinia-CEA vaccine. Clinical cancer research, 6(1), 34-41.
Figure 3 Estimation of anti-CEA Mab internalization by LS174T cells using flow cytometry.
Cells per sample were incubated with 0.1 pg of control ascites only.
Ford, C. H., Tsaltas, G. C., Osborne, P. A., & Addetia, K. (1996). Novel flow cytometric analysis of the progress and route of internalization of a monoclonal anti‐carcinoembryonic antigen (CEA) antibody. Cytometry: The Journal of the International Society for Analytical Cytology, 23(3), 228-240.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-037 | Mouse Anti-CEA Recombinant Antibody (clone MFE-23); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
PFBL-038 | Mouse Anti-CEA Recombinant Antibody (clone T84.66); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
FAMAB-0059-YC-F(E) | Mouse Anti-CEA Recombinant Antibody (clone 2-18); Fab Fragment | IF, FuncS | Mouse Fab |
FAMAB-0060-YC-F(E) | Human Anti-CEA Recombinant Antibody (clone ch2-18); Fab Fragment | IF, FuncS | Human Fab |
HPAB-0631-YJ-F(E) | Mouse Anti-CEA Recombinant Antibody (clone F33-104); Fab Fragment | ELISA, WB | Mouse Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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