Mouse Anti-CEA Recombinant Antibody (clone MFE-23) (CAT#: PABL-037)
Recombinant Mouse Antibody (MFE-23) is capable of binding to CEA, expressed in Chinese Hamster Ovary cells (CHO).
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 Characterization of scFv'-fragments targeting EGFR- or CEA-expressing tumor cells.
Flow cytometry analysis of binding of the two scFv fragments to A549 cells.
Mack, K., Rüger, R., Fellermeier, S., Seifert, O., & Kontermann, R. E. (2012). Dual targeting of tumor cells with bispecific single-chain Fv-immunoliposomes. Antibodies, 1(2), 199-214.
Figure 2 ELISA analyzing the binding of monospecific ILs (hu225-IL, MFE23-IL), dual-targeted immunoliposomes (dt-ILs) as well as non-targeted liposomes (nt) to immobilized CEA and detection of bound liposomes by incubation with EGFR-Fc and an anti-Fc antibody.
Only the dt-ILs caused a signal confirming bispecificity.
Mack, K., Rüger, R., Fellermeier, S., Seifert, O., & Kontermann, R. E. (2012). Dual targeting of tumor cells with bispecific single-chain Fv-immunoliposomes. Antibodies, 1(2), 199-214.
Specifications
- Immunogen
- Human Carcinoembryonic Antigen
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human CEA
- Species Reactivity
- Human
- Clone
- MFE-23
- Applications
- ELISA, WB, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Flow Cytometry and Enzyme-Linked Immunosorbent Assay.
Target
- Alternative Names
- CEA; Carcinoembryonic Antigen
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-037 | Mouse Anti-CEA Recombinant Antibody (clone MFE-23); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
PFBL-038 | Mouse Anti-CEA Recombinant Antibody (clone T84.66); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
HPAB-0569-CN-F(E) | Mouse Anti-CEA Recombinant Antibody; Fab Fragment (HPAB-0569-CN-F(E)) | ELISA, FC | Mouse Fab |
HPAB-0570-CN-F(E) | Human Anti-CEA Recombinant Antibody; Fab Fragment (HPAB-0570-CN-F(E)) | ELISA, FC | Humanized Fab |
HPAB-0571-CN-F(E) | Human Anti-CEA Recombinant Antibody; Fab Fragment (HPAB-0571-CN-F(E)) | ELISA, FC | Human Fab |
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Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# PABL-037, RRID: AB_3111622)
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For Research Use Only. Not For Clinical Use.
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