Mouse Anti-CEA Recombinant Antibody (clone MFE-23) (CAT#: PABL-037)
Recombinant Mouse Antibody (MFE-23) is capable of binding to CEA, expressed in Chinese Hamster Ovary cells (CHO).
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
FC
Figure 1 Characterization of scFv'-fragments targeting EGFR- or CEA-expressing tumor cells.
Flow cytometry analysis of binding of the two scFv fragments to A549 cells.
Mack, K., Rüger, R., Fellermeier, S., Seifert, O., & Kontermann, R. E. (2012). Dual targeting of tumor cells with bispecific single-chain Fv-immunoliposomes. Antibodies, 1(2), 199-214.
ELISA
Figure 2 ELISA analyzing the binding of monospecific ILs (hu225-IL, MFE23-IL), dual-targeted immunoliposomes (dt-ILs) as well as non-targeted liposomes (nt) to immobilized CEA and detection of bound liposomes by incubation with EGFR-Fc and an anti-Fc antibody.
Only the dt-ILs caused a signal confirming bispecificity.
Mack, K., Rüger, R., Fellermeier, S., Seifert, O., & Kontermann, R. E. (2012). Dual targeting of tumor cells with bispecific single-chain Fv-immunoliposomes. Antibodies, 1(2), 199-214.
Specifications
- Immunogen
- Human Carcinoembryonic Antigen
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human CEA
- Species Reactivity
- Human
- Clone
- MFE-23
- Applications
- ELISA, WB, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Flow Cytometry and Enzyme-Linked Immunosorbent Assay.
Target
- Alternative Names
- CEA; Carcinoembryonic Antigen
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-037 | Mouse Anti-CEA Recombinant Antibody (clone MFE-23); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
| PFBL-038 | Mouse Anti-CEA Recombinant Antibody (clone T84.66); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
| HPAB-0569-CN-F(E) | Mouse Anti-CEA Recombinant Antibody; Fab Fragment (HPAB-0569-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0570-CN-F(E) | Human Anti-CEA Recombinant Antibody; Fab Fragment (HPAB-0570-CN-F(E)) | ELISA, FC | Humanized Fab |
| HPAB-0571-CN-F(E) | Human Anti-CEA Recombinant Antibody; Fab Fragment (HPAB-0571-CN-F(E)) | ELISA, FC | Human Fab |
Customer Reviews and Q&As
Customer Review
Q&As
Advanced specificity
This product's antibody specificity is very outstanding. We can now precisely target specific antigens in our assays with the help of it.
Effective
Our workflows are now more productive as a result of using this antibody product. We save time and money because of the excellent quality and dependability.
Essential research
Our research has become dependent on this product to provide the accuracy and dependability required for our intricate investigations.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# PABL-037, RRID: AB_3111622)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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