PE-B*15:02/Human Ubiquitin-conjugating enzyme E2C (ELWKNPTAF) MHC Tetramer
CAT#: MHC-CN0058
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line PC-3
Immunofluorescent staining of human cell line PC-3 shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34569/1216_F6_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35990/265_D2_2_selected.jpg
Normal Tissue
Figure 3 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54975/ihc_selected.jpg
Normal Tissue
Figure 4 IHC staining of human cerebellum
Immunohistochemical staining of human cerebellum shows strong cytoplasmic and nuclear positivity in purkinje cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11464/ihc_selected.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35990/71862_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35990/71862_A_9_8.jpg
Normal Tissue
Figure 7 Tonsil
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Squamous epithelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35990/71862_A_6_8.jpg
Normal Tissue
Figure 8 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35990/71862_A_9_3.jpg
Normal Tissue
Figure 9 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35990/71862_A_7_4.jpg
Normal Tissue
Figure 10 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35990/71862_A_7_5.jpg
RNA Expression
Figure 11 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000175063-UBE2C
❮
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Specifications
- Allele
- B*15:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- Ubiquitin-conjugating enzyme E2C
- Antigen Species
- Human
- Peptide
- ELWKNPTAF
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19. [provided by RefSeq, Aug 2013]
- Alternative Names
- UBE2C; Mitotic-Specific Ubiquitin-Conjugating Enzyme; EC 6.3.2.19; DJ447F3.2; Ubiquitin-Conjugating Enzyme E2C; Ubiquitin Carrier Protein C; Ubiquitin-Protein Ligase C; UBCH10
- Gene ID
- 11065
- UniProt ID
- O00762
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See other products for "UBE2C"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3749 | Rabbit Anti-UBE2C Recombinant Antibody (clone DS3749AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0057 | APC-B*15:02/Human Ubiquitin-conjugating enzyme E2C (ELWKNPTAF) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1285CQ | Mouse Anti-UBE2C Recombinant Antibody (clone SAIC-41C-6) | Immuno-MRM, WB | Mouse IgG1 |
| FAMAB-1286CQ | Mouse Anti-UBE2C Recombinant Antibody (clone SAIC-41A-1) | Immuno-MRM, WB, ELISA | Mouse IgG1 |
| VS3-XY1575 | Mouse Anti-UBE2C Recombinant Antibody (clone 1F5D3) | ELISA, WB, IHC | Mouse IgG2a |
| VS3-XY1576 | Mouse Anti-UBE2C Recombinant Antibody (clone 4C10A7) | ELISA, WB, IHC | Mouse IgG2a |
| VS3-FY1511 | Recombinant Rabbit Anti-UBE2C Antibody (clone R08-4F5) | WB, IHC-Fr, IHC-P, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY524 | Mouse Anti-NHP UBE2C Recombinant Antibody (clone 1F5D3) | WB, ICC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2415 | Anti-UBE2C Immunohistochemistry Kit | IHC | |
| VS-0525-XY7691 | Anti-Rat UBE2C Immunohistochemistry Kit | IHC | |
| VS-0525-XY7690 | Anti-Human UBE2C Immunohistochemistry Kit | IHC |
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