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  • PE-B*15:02/Human Ubiquitin-conjugating enzyme E2C (ELWKNPTAF) MHC Tetramer

PE-B*15:02/Human Ubiquitin-conjugating enzyme E2C (ELWKNPTAF) MHC Tetramer (CAT#: MHC-CN0058)


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Specific Inquiry
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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line PC-3
Figure 1 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34569/1216_F6_1_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35990/265_D2_2_selected.jpg
Normal Tissue
Figure 3 IHC staining of human stomach
Figure 3 IHC staining of human stomach
(Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54975/ihc_selected.jpg
Figure 4 IHC staining of human cerebellum
Figure 4 IHC staining of human cerebellum
(Immunohistochemical staining of human cerebellum shows strong cytoplasmic and nuclear positivity in purkinje cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11464/ihc_selected.jpg
Figure 5 Testis
Figure 5 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35990/71862_A_6_6.jpg
Figure 6 Lymph node
Figure 6 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35990/71862_A_9_8.jpg
Figure 7 Tonsil
Figure 7 Tonsil
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Squamous epithelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35990/71862_A_6_8.jpg
Figure 8 Colon
Figure 8 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35990/71862_A_9_3.jpg
Figure 9 Liver
Figure 9 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35990/71862_A_7_4.jpg
Figure 10 Kidney
Figure 10 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35990/71862_A_7_5.jpg
RNA Expression
Figure 11 RNA cell line category: Low cell line specificity
Figure 11 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000175063-UBE2C

Specifications

  • Allele
  • B*15:02
  • Class
  • Class I
  • Antigen
  • Ubiquitin-conjugating enzyme E2C
  • Antigen Species
  • Human
  • Peptide
  • ELWKNPTAF
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19. [provided by RefSeq, Aug 2013]
  • Alternative Names
  • UBE2C; Mitotic-Specific Ubiquitin-Conjugating Enzyme; EC 6.3.2.19; DJ447F3.2; Ubiquitin-Conjugating Enzyme E2C; Ubiquitin Carrier Protein C; Ubiquitin-Protein Ligase C; UBCH10

Downloads

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Recombinant Antibody

CAT Product Name Application Type
MOB-3665z Mouse Anti-UBE2C Recombinant Antibody (clone 16G12) WB, IHC, IF, ELISA Mouse IgG1
MOB-1197MZ Recombinant Mouse Anti-Human UBE2C Antibody IHC-P, WB Mouse antibody
FAMAB-1285CQ Mouse Anti-UBE2C Recombinant Antibody (clone SAIC-41C-6) Immuno-MRM, WB Mouse IgG1
VS3-QX1211 Mouse Anti-UBE2C Recombinant Antibody (clone 5D-3F) WB, IHC Mouse IgG2a
VS3-CJ117 Mouse Anti-UBE2C Recombinant Antibody (VS3-CJ117) WB Mouse IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3749 Rabbit Anti-UBE2C Recombinant Antibody (clone DS3749AB) WB Rabbit IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-CN0057 APC-B*15:02/Human Ubiquitin-conjugating enzyme E2C (ELWKNPTAF) MHC Tetramer FCM

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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