FITC-H-2 Db/Mouse S protein (CSLWNGPHL) MHC Tetramer

CAT#: MHC-YF1403

This product is a MHC tetramer of biotinylated peptide/MHC complex composed S protein-derived peptide of CSLWNGPHL sequence covering 510-518 and H-2 Db molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.

Specifications

  • Allele
  • H-2 Db
  • Class
  • Class I
  • MHC Species
  • Mouse
  • Antigen
  • S protein
  • Antigen Species
  • MHV
  • Peptide
  • CSLWNGPHL
  • Range
  • 510-518
  • Conjugate
  • FITC
  • Application
  • FCM

Target

  • Antigen Introduction
  • Spike protein S1: attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Interacts with murine CEACAM1 to mediate viral entry.
  • Alternative Names
  • Spike glycoprotein; E2, Peplomer protein
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Breast cancer biomarkers at key points during disease progression
Good for MHV S Protein
This FITC-labeled tetramer helped us identify mouse CD8 T cells specific to the MHV S protein peptide CSLWNGPHL. The signal was distinct, allowing us to track the immune response to the virus in our models.
Breast cancer biomarkers at key points during disease progression
Reliable H-2 Db Reagent
We successfully utilized this product to analyze T cells recognizing the 510-518 region of the Spike protein. The tetramer was stable and provided consistent flow cytometry data for our viral immunology research.

Q&As

  1. Which virus and protein is this tetramer derived from?

    A: The peptide CSLWNGPHL (residues 510-518) is derived from the S protein (Spike glycoprotein) of MHV (Mouse Hepatitis Virus). It is presented by the H-2 Db molecule.

  2. What is the label on this MHC tetramer?

    A: This product is conjugated with Fluorescein isothiocyanate (FITC). It is designed to identify mouse CD8 T cells specific for the MHV S protein peptide using flow cytometry.

View the frequently asked questions answered by Creative Biolabs Support.

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