Human Anti-CCL11 (clone Bertilimumab) scFv-Fc Chimera
CAT#: VS-0425-FY73
This fusion protein targets CCL11 (Eotaxin), a chemokine involved in eosinophil recruitment. It is being explored for its potential use in treating allergic and inflammatory conditions by modulating the immune response.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enriched (BJ hTERT+)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000172156-CCL11
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Specifications
- Host Species
- Human
- Type
- Human IgG4, scFv-Fc
- Specificity
- Human CCL11
- Species Reactivity
- Human
- Clone
- Bertilimumab
- Applications
- ELISA
- Related Disease
- Asthma and Human Immunodeficiency Virus Type 1
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- C-C Motif Chemokine Ligand 11; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 11 (Eotaxin); Chemokine (C-C Motif) Ligand 11; Eosinophil Chemotactic Protein; Eotaxin-1; SCYA11; Small-Inducible Cytokine A11; C-C Motif Chemokine 11; Eotaxin
- Gene ID
- 6356
- UniProt ID
- P51671
- Long Name
- C-C Motif Chemokine Ligand 11
- Sequence Similarities
- Belongs to the intercrine beta (chemokine CC) family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- O-linked glycan consists of a Gal-GalNAc disaccharide which is modified with up to 2 sialic acid residues.
Glycosylation at Thr94
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 2 sites, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_002977.1
- Function
- In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions.
Binds to CCR3.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CCL11"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-1054 | Recombinant Mouse Anti-Human CCL11 Antibody Fab Fragment | ELISA | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-724 | Anti-CCL11 Recombinant Antibody (Bertilimumab) | WB, FC, IP, ELISA, Neut, FuncS, IF | IgG4 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1389MZ | Mouse Anti-CCL11 Recombinant Antibody (clone nythil-FPU2) | ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-108CQ | Mouse Anti-CCL11 Recombinant Antibody (clone CBL162) | Neut, WB, IHC | Mouse IgG1 |
| NEUT-110CQ | Mouse Anti-CCL11 Recombinant Antibody (clone CBL469) | WB, IHC, ELISA(Cap), Neut | Mouse IgG1 |
| NEUT-111CQ | Mouse Anti-CCL11 Recombinant Antibody (NEUT-111CQ) | IHC, Neut, WB | Mouse IgG1 |
| NEUT-112CQ | Rat Anti-CCL11 Recombinant Antibody (clone CBL166) | IHC, Neut, WB | Rat IgG2 |
| NEUT-113CQ | Rat Anti-CCL11 Recombinant Antibody (clone CBL779) | WB, IHC, Neut | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-109CQ | Rat Anti-CCL11 Recombinant Antibody (NEUT-109CQ) | Block, ELISA | Rat IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0501 | Hi-Affi™ Rabbit Anti-CCL11 Recombinant Antibody (clone DS501AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-724 | Afuco™ Anti-CCL11 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-724) | FC, IP, ELISA, Neut, FuncS | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1053 | Anti-Mouse CCL11 Immunohistochemistry Kit | IHC |
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