Anti-CCL11 Recombinant Antibody (Bertilimumab) (CAT#: TAB-724)
Recombinant human monoclonal antibody expressed in CHO binding to human CCL11. Bertilimumab is a human monoclonal antibody that binds to eotaxin-1, an important regulator of overall eosinophil function. It was to be used to treat severe allergic disorders.
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RNA Expression
Figure 1 RNA cell line category: Cell line enriched (BJ hTERT+)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000172156-CCL11
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000172156-CCL11
Figure 1 RNA cell line category: Cell line enriched (BJ hTERT+)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000172156-CCL11
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000172156-CCL11
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG4 - kappa
- Species Reactivity
- Human
- Applications
- Suitable for use in ELISA, Neut, IF, IP, FC, FuncS and most other immunological methods.
- Trade name
- cat-213
- CAS
- 375348-49-5
- Generic Name
- bertilimumab
- Related Disease
- Allergies, severe ocular
Product Property
- Purity
- >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- bertilimumab;cat-213;375348-49-5;CAT-213;CAT213;iCo-008;CAT-212;CCL11;chemokine (C-C motif) ligand 11;SCYA11, small inducible cytokine subfamily A (Cys Cys), member 11 (eotaxin);eotaxin;eotaxin 1;MGC22554;eotaxin-1;C-C motif chemokine 11;small-inducible c
- Gene ID
- 6356
- UniProt ID
- P51671
Related Resources
Please refer to Bertilimumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Bertilimumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Bertilimumab"
Afuco™ Anti-CCL11 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-724)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant human monoclonal antibody expressed in CHO binding to human CCL11. It is a human monoclonal antibody that binds to eotaxin-1, an important regulator of overall eosinophil function. It was to be used to treat severe allergic disorders.
DrugMonitor™ Anti-Bertilimumab Antibody (VS-1224-YC187)Bertilimumab is a fully human anti-eotaxin monoclonal antibody, initially developed for treating allergic disorders, currently in pre-clinical development for Allergic Rhinitis treatment. The DrugMonitor™ Anti-Bertilimumab Antibody (VS-1224-YC187) is an anti-drug antibody (ADA) against Bertilimumab. This drug-based antibody is raised in mice immunized with the Bertilimumab. The anti-Bertilimumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Bertilimumab in samples.
See other products for "CCL11"
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ADCC Enhanced Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-1054 | Recombinant Mouse Anti-Human CCL11 Antibody Fab Fragment | ELISA | Fab |
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Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-724, RRID: AB_3111992)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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