Human Anti-CD55 (clone LU30) scFv-Fc Chimera (CAT#: VS-0325-FY204)
The anti-CD55 scFv-Fc antibody targets CD55 (Decay-accelerating factor), a complement regulatory protein involved in immune response and inflammation. This antibody provides specific targeting of CD55, with potential applications in research related to complement activation, immune regulation, and its role in autoimmune and inflammatory diseases.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_B_8_5.jpg
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_B_8_5.jpg
Figure 2 Lung
(Alveolar cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_1_4.jpg
(Alveolar cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_1_4.jpg
Figure 3 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_8_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_8_3.jpg
Figure 4 Testis
(Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_4_6.jpg
(Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24386/54385_A_4_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (HeLa, HMC-1, PC-3, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196352-CD55
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196352-CD55
Figure 5 RNA cell line category: Cell line enhanced (HeLa, HMC-1, PC-3, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196352-CD55
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196352-CD55
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human CD55
- Species Reactivity
- Human
- Clone
- LU30
- Applications
- Flow Cytometry, ELISA
- Related Disease
- Lung cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- ELISA: 3 μg/mL
Target
- Alternative Names
- CD55 Molecule (Cromer Blood Group); CD55 Molecule, Decay Accelerating Factor For Complement (Cromer Blood Group); CD55 Antigen; DAF; CR; Decay Accelerating Factor For Complement (CD55, Cromer Blood Group System)
- Gene ID
- 1604
- UniProt ID
- P08174
- Long Name
- CD55 Molecule (Cromer Blood Group)
- Sequence Similarities
- Belongs to the receptors of complement activation (RCA) family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- The Ser/Thr-rich domain is heavily O-glycosylated.
Glycosylation at Asn95, Thr343, and Thr344
Modification sites at PhosphoSitePlus
Glycosylation from GlyConnect DAF_HUMAN (1151)
Glycosylation from GlyGen 6 sites, 13 N-linked glycans (1 site), 2 O-linked glycans (5 sites)
- Protein Refseq
- XP_054190684.1; XP_054190685.1; NP_000565.1; NP_001108224.1; NP_001287831.1
- Function
- Human CD55, also known as decay-accelerating factor (DAF), is a membrane protein that protects cells from complement-mediated damage. It plays a role in immune regulation and is implicated in autoimmune diseases.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-316LC | Human Anti-CD55 Recombinant Antibody (TAB-316LC) | ELISA, FC, Inhib | Human IgG1 |
| TAB-316LC-S(P) | Human Anti-CD55 Recombinant Antibody; scFv Fragment (TAB-316LC-S(P)) | ELISA | Human scFv |
| TAB-316LC-F(E) | Human Anti-CD55 Recombinant Antibody; Fab Fragment (TAB-316LC-F(E)) | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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