Human Anti-CD55 (clone LU30) scFv-Fc Chimera

CAT#: VS-0325-FY204

The anti-CD55 scFv-Fc antibody targets CD55 (Decay-accelerating factor), a complement regulatory protein involved in immune response and inflammation. This antibody provides specific targeting of CD55, with potential applications in research related to complement activation, immune regulation, and its role in autoimmune and inflammatory diseases.

Gene Expression
Figure 1 Cerebral cortex Figure 2 Lung Figure 3 Colon Figure 4 Testis Figure 5 RNA cell line category: Cell line enhanced (HeLa, HMC-1, PC-3, U-2197)

Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1, scFv-Fc
  • Specificity
  • Human CD55
  • Species Reactivity
  • Human
  • Clone
  • LU30
  • Applications
  • Flow Cytometry, ELISA
  • Related Disease
  • Lung cancer

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • ELISA: 3 μg/mL

Target

  • Alternative Names
  • CD55 Molecule (Cromer Blood Group); CD55 Molecule, Decay Accelerating Factor For Complement (Cromer Blood Group); CD55 Antigen; DAF; CR; Decay Accelerating Factor For Complement (CD55, Cromer Blood Group System)
  • Long Name
  • CD55 Molecule (Cromer Blood Group)
  • Sequence Similarities
  • Belongs to the receptors of complement activation (RCA) family.
  • Cellular Localization
  • Cell membrane
  • Post Translation Modifications
  • The Ser/Thr-rich domain is heavily O-glycosylated.
    Glycosylation at Asn95, Thr343, and Thr344
    Modification sites at PhosphoSitePlus
    Glycosylation from GlyConnect DAF_HUMAN (1151)
    Glycosylation from GlyGen 6 sites, 13 N-linked glycans (1 site), 2 O-linked glycans (5 sites)
  • Function
  • Human CD55, also known as decay-accelerating factor (DAF), is a membrane protein that protects cells from complement-mediated damage. It plays a role in immune regulation and is implicated in autoimmune diseases.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

Certificate of Analysis Lookup

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Secondary Antibody

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