Human Anti-FCGRT scFv-Fc Chimera (VS-0325-FY184)
CAT#: VS-0325-FY184
The anti-FcRn scFv-Fc antibody targets the neonatal Fc receptor (FcRn), which plays a crucial role in IgG homeostasis and immune response. This antibody is designed to provide specific targeting of FcRn, with potential applications in research related to IgG metabolism, immune tolerance, and the development of therapeutic strategies targeting FcRn-mediated pathways.

Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human FCGRT
- Species Reactivity
- Human
- Applications
- ELISA
- Related Disease
- Autoimmune Disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Fc Fragment Of IgG Receptor And Transporter; Heavy Chain Of The Major Histocompatibility Complex Class I-Like Fc Receptor; Transmembrane Alpha Chain Of The Neonatal Receptor; Fc Fragment Of IgG, Receptor, Transporter, Alpha; IgG Fc Fragment Receptor Transporter Alpha Chain; Neonatal Fc Receptor; FCRN
- Gene ID
- 2217
- UniProt ID
- P55899
- Long Name
- Fc Fragment Of IgG Receptor And Transporter
- Sequence Similarities
- Belongs to the immunoglobulin superfamily.
- Cellular Localization
- Cell membrane; Endosome membrane
- Post Translation Modifications
- Glycosylation at Asn125
Modification sites at PhosphoSitePlus
Glycosylation from GlyConnect FCGRN_HUMAN (1387)
Glycosylation from GlyGen 2 sites, 48 N-linked glycans (1 site), 1 O-linked glycan (1 site)
- Protein Refseq
- XP_047294364.1; XP_047294366.1; XP_047294367.1; XP_047294368.1; XP_054176174.1
- Function
- Human FCGRT (Fc receptor, IgG, neonatal) is an Fc receptor that plays a crucial role in IgG antibody recycling and transport. It influences antibody half-life and is a target for therapeutic modulation of IgG levels.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1102z | Mouse Anti-FCGRT Recombinant Antibody (MOB-1102z) | ELISA, WB, IP, IF, IHC, FC | Mouse IgG2a, κ |
HPAB-1786LY | Human Anti-FCGRT Recombinant Antibody (HPAB-1786LY) | ELISA | Human IgG |
HPAB-1787LY | Mouse Anti-FCGRT Recombinant Antibody (HPAB-1787LY) | ELISA | Mouse IgG |
HPAB-1788LY | Mouse Anti-FCGRT Recombinant Antibody (HPAB-1788LY) | ELISA | Mouse IgG |
HPAB-1789LY | Mouse Anti-FCGRT Recombinant Antibody (HPAB-1789LY) | ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1102z-F(E) | Recombinant Anti-Human FCGRT Antibody Fab Fragment | WB, FACS, FuncS | Fab |
HPAB-1786LY-F(E) | Human Anti-FCGRT Recombinant Antibody; Fab Fragment (HPAB-1786LY-F(E)) | ELISA | Human Fab |
HPAB-1787LY-F(E) | Mouse Anti-FCGRT Recombinant Antibody; Fab Fragment (HPAB-1787LY-F(E)) | ELISA | Mouse Fab |
HPAB-1788LY-F(E) | Mouse Anti-FCGRT Recombinant Antibody; Fab Fragment (HPAB-1788LY-F(E)) | ELISA | Mouse Fab |
PFBC-246 | Human Anti-FCGRT Recombinant Antibody; Fab Fragment (PFBC-246) | ELISA, FC, Block | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-042WM | Human Anti-FCGRT Recombinant Antibody (TAB-042WM) | FC | Human antibody |
TAB-042WM-S(P) | Human Anti-FCGRT Recombinant Antibody; scFv Fragment (TAB-042WM-S(P)) | FC | Human scFv |
TAB-042WM-F(E) | Human Anti-FCGRT Recombinant Antibody; Fab Fragment (TAB-042WM-F(E)) | FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4173 | Hi-Affi™ Rabbit Anti-FCGRT Recombinant Antibody (clone SI250DS) | IHC-P | Rabbit IgG |
MOR-4387 | Hi-Affi™ Rabbit Anti-Fcgrt Recombinant Antibody (clone SI478DS) | ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-450CQ | Anti-Human FCGRT Recombinant Antibody (TAB-450CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG4, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0199-CN-S(P) | Human Anti-FCGRT Recombinant Antibody; scFv Fragment (HPAB-0199-CN-S(P)) | FC | Human scFv |
HPAB-0200-CN-S(P) | Human Anti-FCGRT Recombinant Antibody; scFv Fragment (HPAB-0200-CN-S(P)) | ELISA, FC | Human scFv |
HPAB-0201-CN-S(P) | Human Anti-FCGRT Recombinant Antibody; scFv Fragment (HPAB-0201-CN-S(P)) | ELISA, FC | Human scFv |
HPAB-0202-CN-S(P) | Human Anti-FCGRT Recombinant Antibody; scFv Fragment (HPAB-0202-CN-S(P)) | FC | Human scFv |
HPAB-1786LY-S(P) | Human Anti-FCGRT Recombinant Antibody; scFv Fragment (HPAB-1786LY-S(P)) | ELISA | Human scFv |
CAT | Product Name | Application | Type |
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AFC-TAB-450CQ | Afuco™ Anti-FCGRT ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-450CQ) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
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VS-0425-YC338 | Recombinant Anti-FCGRT Vesicular Antibody, EV Displayed (VS-0425-YC338) | ELISA, FC, Cell-uptake |
CAT | Product Name | Application | Type |
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VS-0525-XY2488 | Anti-FCGRT Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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