Human Anti-IL18RAP scFv-Fc Chimera (VS-0425-FY5)
CAT#: VS-0425-FY5
This product can be utilized in research to study the role of IL18RAP in immune responses, as well as in therapeutic developments for conditions associated with dysregulated IL-18 signaling, including autoimmune diseases, chronic inflammation, and certain cancers.
Gene Expression
Normal Tissue
Figure 1 Bone marrow
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25270/161339_B_4_4_val_selected.jpg
Normal Tissue
Figure 2 Lymph node
Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25270/161421_A_7_8.jpg
Normal Tissue
Figure 3 Tonsil
Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25270/161421_A_6_8.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enriched (U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115607-IL18RAP
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Specifications
- Immunogen
- The immunogen was human IL-18Rβ.
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human IL18RAP
- Species Reactivity
- Human
- Applications
- Blocking, ELISA, Immunofluorescence, Flow Cytometry
- Related Disease
- Crohn's disease and inflammatory bowel disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- Interleukin 18 Receptor Accessory Protein
- Gene ID
- 8807
- UniProt ID
- O95256
- Long Name
- Interleukin 18 Receptor Accessory Protein
- Sequence Similarities
- Belongs to the interleukin-1 receptor family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- N-glycosylated.
Glycosylation at Asn152, Asn21, Asn119, and Asn345
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 4 sites
- Protein Refseq
- XP_011510390.1; XP_024308965.1; XP_024308966.1; XP_024308967.1; XP_024308969.1
- Function
- Induced by IFN-alpha and IL12/interleukin-12 in natural killer (NK) cells and T-cells.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "IL18RAP"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1928z | Mouse Anti-IL18RAP Recombinant Antibody (clone 22B8) | WB, IHC, FuncS | Mouse IgG1 |
| MOB-0234CT | Recombinant Mouse anti-Human IL18RAP Monoclonal antibody (EML2092) | WB | |
| PABJ-0032 | Human Anti-IL18RAP Recombinant Antibody (clone 3131) | ELISA, Inhib | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1251CQ | Mouse Anti-IL18RAP Recombinant Antibody (clone CBL328) | Neut, WB | Mouse IgG1 |
| NEUT-1252CQ | Mouse Anti-IL18RAP Recombinant Antibody (NEUT-1252CQ) | Neut, WB | Mouse IgG1 |
| NEUT-1253CQ | Mouse Anti-IL18RAP Recombinant Antibody (clone CBL120) | Neut, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABJ-0032-S(P) | Human Anti-IL18RAP Recombinant Antibody (clone 3131); scFv Fragment | ELISA, Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABJ-0032-F(E) | Human Anti-IL18RAP Recombinant Antibody (clone 3131); Fab fragment | ELISA, Inhib | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC418 | Recombinant Anti-IL18RAP Vesicular Antibody, EV Displayed (VS-0425-YC418) | ELISA, FC, Inhib, Cell-uptake |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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