Human Anti-IL18RAP scFv-Fc Chimera (VS-0425-FY5) (CAT#: VS-0425-FY5)
This product can be utilized in research to study the role of IL18RAP in immune responses, as well as in therapeutic developments for conditions associated with dysregulated IL-18 signaling, including autoimmune diseases, chronic inflammation, and certain cancers.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Bone marrow
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25270/161339_B_4_4_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25270/161339_B_4_4_val_selected.jpg
Figure 2 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25270/161421_A_7_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25270/161421_A_7_8.jpg
Figure 3 Tonsil
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25270/161421_A_6_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/25270/161421_A_6_8.jpg
Figure 4 RNA cell line category: Cell line enriched (U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115607-IL18RAP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115607-IL18RAP
Specifications
- Immunogen
- The immunogen was human IL-18Rβ.
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human IL18RAP
- Species Reactivity
- Human
- Applications
- Blocking, ELISA, Immunofluorescence, Flow Cytometry
- Related Disease
- Crohn's disease and inflammatory bowel disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- Interleukin 18 Receptor Accessory Protein
- Gene ID
- 8807
- UniProt ID
- O95256
- Long Name
- Interleukin 18 Receptor Accessory Protein
- Sequence Similarities
- Belongs to the interleukin-1 receptor family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- N-glycosylated.
Glycosylation at Asn152, Asn21, Asn119, and Asn345
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 4 sites
- Protein Refseq
- XP_011510390.1; XP_024308965.1; XP_024308966.1; XP_024308967.1; XP_024308969.1
- Function
- Induced by IFN-alpha and IL12/interleukin-12 in natural killer (NK) cells and T-cells.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "IL18RAP"
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1928z | Mouse Anti-IL18RAP Recombinant Antibody (clone 22B8) | WB, IHC, FuncS | Mouse IgG1 |
| MOB-0234CT | Recombinant Mouse anti-Human IL18RAP Monoclonal antibody (EML2092) | WB | |
| PABJ-0032 | Human Anti-IL18RAP Recombinant Antibody (clone 3131) | ELISA, Inhib | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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