Recombinant Human Anti-MART1 Soluble TCR (T1-S18) (KIH) (CAT#: VS-0622-YF6532)
Human TCR (T1-S18) recognizes MART1 peptide (ELAGIGILTV) in the context of HLA-A*02:01. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in skin 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_B_8_1_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_B_8_1_val_selected.jpg
Figure 2 Low expression in liver
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_8_4_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_8_4_val_selected.jpg
Figure 3 Testis
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_5_6.jpg
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_5_6.jpg
Figure 4 RNA cell line category: Cell line enriched (SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120215-MLANA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120215-MLANA
Specifications
- Host Species
- Human
- Target
- MART1
- Species Reactivity
- Human
- Epitope
- ELAGIGILTV
- MHC
- HLA-A*02:01
- Clone
- T1-S18
- Type
- Soluble TCR (KIH)
- Related Disease
- Melanoma
- TCR Expression Strategy
- KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).
Target
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1380z | Mouse Anti-MLANA Recombinant Antibody (clone 22A7) | ELISA, FC, ICC, IF, IHC, WB | Mouse IgG1 |
| MRO-0987-CN | Recombinant Rabbit Anti-MLANA Monoclonal Antibody (CBACN-366) | WB, IHC, FC | Rabbit IgG |
| MOB-0096F | Mouse Anti-MLANA Recombinant Antibody (MOB-0096F) | IHC-P, IF | Mouse IgG |
| ZG-494C | Mouse Anti-MLANA Recombinant Antibody (clone 87.1.1) | ELISA, WB, IHC | Mouse IgG1, κ |
| VS3-XY1075 | Mouse Anti-MLANA Recombinant Antibody (clone 2F3B7) | ELISA, WB | Mouse IgG1 |
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