Recombinant Human Anti-MLANA Soluble TCR (α24β17) (KIH) (CAT#: VS-0622-YF7410)
Human TCR (α24β17) recognizes MLANA peptide (ALAGIGILTV) in the context of HLA-A*02:01. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in skin 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_B_8_1_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_B_8_1_val_selected.jpg
Figure 2 Low expression in liver
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_8_4_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_8_4_val_selected.jpg
Figure 3 Testis
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_5_6.jpg
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_A_5_6.jpg
Figure 4 RNA cell line category: Cell line enriched (SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120215-MLANA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120215-MLANA
Specifications
- Host Species
- Human
- Target
- MLANA
- Species Reactivity
- Human
- Epitope
- ALAGIGILTV
- MHC
- HLA-A*02:01
- Clone
- α24β17
- Type
- Soluble TCR (KIH)
- Related Disease
- Melanoma
- TCR Expression Strategy
- KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).
Target
- Alternative Names
- Melan-A; Antigen LB39-AA; Antigen SK29-AA; Protein Melan-A; MART-1; MART1; Melanoma Antigen Recognized By T-Cells 1
- Gene ID
- 2315
- UniProt ID
- Q16655
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1380z | Mouse Anti-MLANA Recombinant Antibody (clone 22A7) | ELISA, FC, ICC, IF, IHC, WB | Mouse IgG1 |
| MRO-0987-CN | Recombinant Rabbit Anti-MLANA Monoclonal Antibody (CBACN-366) | WB, IHC, FC | Rabbit IgG |
| VS3-XY1075 | Mouse Anti-MLANA Recombinant Antibody (clone 2F3B7) | ELISA, WB | Mouse IgG1 |
| VS3-XY1076 | Mouse Anti-MLANA Recombinant Antibody (clone 2F1) | ELISA, WB | Mouse IgG1 |
| VS3-FY930 | Recombinant Mouse Anti-MLANA Antibody (clone 4A9-1E7-10H2) | IHC-P | Mouse IgG2b |
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