Human Anti-MMP12 scFv-Fc Chimera (VS-0325-FY102) (CAT#: VS-0325-FY102)
The anti-MMP12 scFv-Fc antibody targets MMP12 (Matrix Metalloproteinase 12), an enzyme involved in elastin and collagen degradation. It has potential therapeutic applications in diseases associated with MMP12 overactivity, such as chronic obstructive pulmonary disease (COPD)and fibrosis. The scFv-Fc format enhances its stability and bioavailability, making it suitable for prolonged therapeutic use.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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RNA Expression
Figure 1 RNA cell line category: Group enriched.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000262406-MMP12
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000262406-MMP12
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human MMP12
- Species Reactivity
- Human
- Applications
- ELISA
- Related Disease
- Chronic obstructive pulmonary disease (COPD) and fibrosis
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Matrix Metallopeptidase 12; Matrix Metalloproteinase 12 (Macrophage Elastase); Macrophage Elastase; EC 3.4.24.65; MMP-12; HME; MME
- Gene ID
- 4321
- UniProt ID
- P39900
- Long Name
- Matrix Metallopeptidase 12
- Sequence Similarities
- Belongs to the peptidase M10A family.
- Cellular Localization
- Extracellular matrix; Secreted
- Protein Refseq
- NP_002417.2
- Function
- May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3728z | Mouse Anti-MMP12 Recombinant Antibody (clone 19D6) | WB, IP, IF, ELISA | Mouse IgG2b |
| MOB-1940MZ | Recombinant Mouse Anti-Human MMP12 Antibody | IHC-P, WB | Mouse antibody |
| MRO-1008-CN | Recombinant Rabbit Anti-MMP12 Monoclonal Antibody (CBACN-376) | WB, IF, IHC, IP, FC | Rabbit IgG |
| VS3-CJ926 | Rabbit Anti-MMP12 Recombinant Antibody (VS3-CJ926) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
| VS3-FY937 | Recombinant Rabbit Anti-MMP12 Antibody (clone R03-2B9) | WB, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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