Human Anti-TIGIT scFv-Fc Chimera (VS-0325-FY8) (CAT#: VS-0325-FY8)

• Host Species
• Human

• Type
• Human IgG1, scFv-Fc

• Specificity
• Human TIGIT

• Species Reactivity
• Human

• Applications
• ELISA

• Related Disease
• Cancer

• Purity
• >95% as determined by SDS-PAGE

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Ice packs

• Alternative Names
• T Cell Immunoreceptor With Ig And ITIM Domains; V-Set And Immunoglobulin Domain-Containing Protein 9; V-Set And Transmembrane Domain-Containing Protein 3; T-Cell Immunoreceptor With Ig And ITIM Domains; VSIG9, VSTM3; VSIG9

• Gene ID
• 201633

• UniProt ID
• Q495A1

• Long Name
• T Cell Immunoreceptor With Ig And ITIM Domains

• Cellular Localization
• Cell membrane

• Post Translation Modifications
• Glycosylation at Asn32 and Asn101
  Modification sites at PhosphoSitePlus
  Glycosylation from GlyGen 2 sites

• Protein Refseq
• XP_047303627.1; XP_047303628.1; XP_054201627.1; XP_054201628.1; XP_054201629.1

• Function
• Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Isotype Control

• MOB-200CQ
• Human IgG Fc Isotype Control Antibody

Secondary Antibody

• 2ND-029CQ
• Goat Anti-Human IgG Fc Antibody

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