Human Anti-TNFRSF13C scFv-Fc Chimera (VS-0425-FY34) (CAT#: VS-0425-FY34)
anti-TNFRSF13C scFv-Fc antibody is a monoclonal antibody targeting TNFRSF13C (TNF receptor superfamily member 13C). TNFRSF13C plays a significant role in various diseases, including autoimmune diseases and certain types of cancer. The antibody specifically binds to TNFRSF13C through its single-chain variable fragment (scFv) domain, and the Fc fragment endows it with the ability to interact with immune effector molecules such as Fc receptors and the complement system. This antibody has potential applications in studying the function and mechanism of TNFRSF13C and may serve as a potential target for treating related diseases.
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Normal Tissue
RNA Expression
Figure 1 Colon
(Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8380/19871_A_7_3.jpg
(Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8380/19871_A_7_3.jpg
Figure 2 Lymph node
(Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8380/19871_A_9_8.jpg
(Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8380/19871_A_9_8.jpg
Figure 3 RNA cell line category: Group enriched (REH, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000159958-TNFRSF13C
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000159958-TNFRSF13C
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human TNFRSF13C
- Species Reactivity
- Human
- Applications
- Immunoassay
- Related Disease
- Immunodeficiency, Common Variable, 4 and Common Variable Immunodeficiency
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- TNF Receptor Superfamily Member 13C; BLyS Receptor 3; BAFF Receptor; BAFF-R; BAFFR; Tumor Necrosis Factor Receptor Superfamily, Member 13C; Tumor Necrosis Factor Receptor Superfamily Member 13C; B Cell-Activating Factor Receptor
- Gene ID
- 115650
- UniProt ID
- Q96RJ3
- Long Name
- TNF Receptor Superfamily Member 13C
- Cellular Localization
- Membrane
- Post Translation Modifications
- Modification sites at PhosphoSitePlus
Modification sites at neXtProt
Glycosylation from GlyGen 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_443177.1
- Function
- B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS.
Promotes the survival of mature B-cells and the B-cell response.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-2273-sdAb | Recombinant Anti-human TNFRSF13C VHH Single Domain Antibody | ICC, FC, WB, FUNC | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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