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    Mouse Anti-BRCA1 Recombinant Antibody (clone 6C6D2) (CAT#: VS3-XY137)

    Clone 6C6D2 is a mouse antibody, which reacts with human BRCA1 protein. This antibody is suitable for BRCA1 detection by ELISA, WB, IHC assays.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
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    Conjugation :
    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line RH-30
    Figure 1 IF staining of human cell line RH-30
    (Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm & nuclear bodies.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4840/1914_E5_15_cr5c8770e98e94d_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human testis
    Figure 2 IHC staining of human testis
    (Immunohistochemical staining of human testis shows strong nuclear positivity in a subset of cells in seminiferous ducts.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/34966/89241_A_4_6_selected.jpg
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Neuronal cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1946/5290_B_8_5.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1946/5290_A_9_3.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Cells in seminiferous ducts
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous nuclear
    Leydig cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1946/5290_A_6_6.jpg
    Figure 6 Skin
    Figure 6 Skin
    (Epidermal cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1946/5290_B_5_8.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Nuclear
    Non-germinal center cells
    Staining: Medium
    Intensity: Strong
    Quantity: <25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1946/5290_A_8_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000012048-BRCA1

    Specifications

    • Immunogen
    • Recombinant fragment of human BRCA1 (a.a. 229-335) expressed in E. coli.
    • Host Species
    • Mouse
    • Type
    • Mouse IgG1
    • Specificity
    • Human BRCA1
    • Species Reactivity
    • Human
    • Clone
    • 6C6D2
    • Applications
    • Enzyme-linked Immunosorbent Assay, Western Blot, Immunohistochemistry

    Product Property

    • Purification
    • Affinity purified
    • Format
    • Liquid
    • Buffer
    • PBS
    • Preservative
    • 0.05% sodium azide
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • This antibody is recommended for Western Blot (1/500-1/2000), Enzyme-linked Immunosorbent Assay (1/10000) and Immunohistochemistry(1/200-1/1000).

    Target

    • Alternative Names
    • BRCA1, DNA Repair Associated; Protein Phosphatase 1, Regulatory Subunit 53; BRCA1/BRCA2-Containing Complex, Subunit 1; Fanconi Anemia, Complementation Group S; Breast Cancer 1, Early Onset; RING Finger Protein 53; RNF53; Breast And Ovarian Cancer Susceptibility Protein 1; Breast Cancer Type 1 Susceptibility Protein; RING-Type E3 Ubiquitin Transferase BRCA1; Early Onset Breast Cancer 1; Breast Cancer 1

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "BRCA1"

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    CAT Product Name Application Type
    MOB-123 Recombinant Anti-human BRCA1 Antibody ELISA, WB, Neut, FuncS IgG
    MHH-123 Recombinant Human Anti-human BRCA1 Antibody FC, ELISA, FuncS IgG
    MOB-1473MZ Mouse Anti-BRCA1 Recombinant Antibody (clone 7C5) IP, WB Mouse IgG1
    VS3-WK1325 Mouse Anti-BRCA1 Recombinant Antibody (VS3-WK1325) ELISA, WB Mouse IgG

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