Recombinant Mouse Anti-Matrix M2 Soluble TCR (TRBV13-2) (KIH)
CAT#: VS-0622-YF6484
Mouse TCR (TRBV13-2) recognizes Matrix M2 peptide (SYIGSINNI) in the context of H-2Kd. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.
Specifications
- Host Species
- Mouse
- Target
- Matrix M2
- Species Reactivity
- Respiratory Syncytial Virus
- Epitope
- SYIGSINNI
- MHC
- H-2Kd
- Clone
- TRBV13-2
- Type
- Soluble TCR (KIH)
- Related Disease
- Colorectal cancer
- TCR Expression Strategy
- KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).
Target
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Good For RSV Studies
We purchased this mouse TCR to study the Matrix M2 protein from Respiratory Syncytial Virus. The TRBV13-2 clone recognized the SYIGSINNI peptide in the H-2Kd context, which was critical for our viral protein research.
Stable Heterodimer Format
The Knob-in-hole strategy provided a stable heterodimer for our assays. This product was instrumental in our colorectal cancer research involving the Matrix M2 peptide, offering reliable binding without aggregation issues.
Q&As
-
What is the target of the TRBV13-2 clone?
A: The TRBV13-2 clone is a mouse TCR that targets the Matrix M2 protein of the Respiratory Syncytial Virus. Specifically, it recognizes the peptide sequence SYIGSINNI in the context of H-2Kd.
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Does this product contain the transmembrane region?
A: No, in this KIH strategy product, the soluble TCR contains the single chain TCR where the VL/VH regions are replaced with Valpha-linker-Vbeta. It is expressed as a soluble heterodimer without transmembrane regions.
View the frequently asked questions answered by Creative Biolabs Support.
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