Mouse Anti-PTPRJ scFv-Fc Chimera (VS-0325-FY43)

CAT#: VS-0325-FY43

The anti-CD148 scFv-Fc antibody targets CD148, a receptor-like tyrosine phosphatase involved in cell signaling and immune regulation. It is designed to modulate CD148 function, which may have therapeutic implications in autoimmune and inflammatory diseases.

Gene Expression
Figure 1 IHC staining of human tonsil Figure 2 RNA cell line category: Cell line enhanced (RPTEC TERT1)

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG1, scFv-Fc
  • Specificity
  • The antibody binds to a peptide having the sequence of amino acid residues 324-338 and 321-335, but does not bind to an octapeptide having the sequence of amino acid residues 324-331 of human CD148.
  • Species Reactivity
  • Human
  • Applications
  • ELISA

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Target

  • Alternative Names
  • PTPRJ, CD148, DEP1, HPTPeta, R-PTP-ETA, SCC1, protein tyrosine phosphatase, receptor type J, protein tyrosine phosphatase receptor type J, R-PTP-J, HPTP eta
  • Long Name
  • Receptor-type tyrosine-protein phosphatase eta
  • Sequence Similarities
  • Belongs to the protein-tyrosine phosphatase family.
  • Cellular Localization
  • Cell membrane
  • Post Translation Modifications
  • N- and O-glycosylated.
    N-glycosylated.
    Glycosylation at Asn72, Asn82, Asn93, Asn104, Asn142, Asn172, Asn192, Asn231, Asn258, Asn278, Asn342, Asn351, Asn376, Asn391, Asn396, Asn413, Asn431, Asn501, Asn525, Asn536, Asn582, Asn603, Asn618, Asn628, Asn637, Asn666, Asn669, Asn761, Asn772, Asn784, Asn790, Asn824, Asn910, and Asn937
    Modification sites at PhosphoSitePlus
    Glycosylation from GlyConnect PTPRJ_HUMAN (1707)
    Glycosylation from GlyGen 44 sites, 41 N-linked glycans (18 sites), 3 O-linked glycans (7 sites)
  • Function
  • PTPRJ (Protein tyrosine phosphatase receptor type J) is a cell surface phosphatase that regulates various signaling pathways. It influences cell growth, adhesion, and migration, and its dysfunction is associated with cancer.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

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Secondary Antibody

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