Myofibroblast / Fibrosis Antibody Panel (ACTA2, Collagen I, FN1)

CAT#: VS-0725-YC12

The Myofibroblast / Fibrosis Antibody Panel features 3 highly validated antibodies, precisely chosen for the simultaneous detection of key markers associated with myofibroblast activation and fibrotic processes. Included in this targeted set are antibodies against ACTA2, Collagen I, and FN1. This panel offers a streamlined approach to characterize fibrosis across various organ systems, providing reliable data for your research into disease pathology and therapeutic interventions.

Sub Cat Component Name Clone Type Target Species Reactivity Applications  
HPAB-S0038-YC Human Anti-FN1 Recombinant Antibody (clone L19) L19 Human IgG FN1 Human ELISA, IF, IHC
VS3-QX13 Mouse Anti-ACTA2 Recombinant Antibody (clone 7F12) 7F12 Mouse IgG1 ACTA2 Human, Mouse, Rat, Monkey WB, IHC, ICC, FC, ELISA
TAB-053MZ Mouse Anti-Collagen I (RGD motif) Recombinant Antibody (TAB-053MZ) Mouse IgG1, κ Collagen I (RGD motif) Human, Mouse WB, IF, FuncS
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Specifications

  • Targets
  • ACTA2, Collagen I, FN1
  • Species Reactivity
  • Human
  • Research Area
  • Myofibroblast and Fibrosis
  • Introduction
  • Myofibroblasts are a distinctive cell type characterized by features intermediate between fibroblasts and smooth muscle cells. These versatile cells play a pivotal role in tissue repair, wound healing, and crucially, in the pathological process of fibrosis. They are identified by their robust contractile machinery, including the expression of α-smooth muscle actin (α-SMA, encoded by ACTA2), and their vigorous capacity to synthesize and remodel extracellular matrix (ECM) components, particularly Collagen I and
  • Storage
  • Store at 4°C for up to a week. For long-term storage, store at -20°C or below.
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