Recombinant Anti-ACE2 Vesicular Antibody, EV Displayed (VS-0425-YC18)
CAT#: VS-0425-YC18
The Recombinant Anti-ACE2 Vesicular Antibody, EV Displayed (VS-0425-YC18) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ACE2-expressed cells or tissues. The ACE2 is a protein from the angiotensin-converting enzyme family, catalyzing the conversion of angiotensin I and II into functional forms. It plays roles in cardiovascular, renal, and fertility regulation and serves as a receptor for SARS and HCoV-NL63 coronaviruses.
Gene Expression
Normal Tissue
Figure 1 Small intestine
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/288/170349_A_6_2_val_selected.jpg
Normal Tissue
Figure 2 Colon
Enterocytes - Microvilli Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/288/170349_A_9_3.jpg
Normal Tissue
Figure 3 Kidney
Bowman's capsule Staining: Medium Intensity: Strong Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/288/170349_A_7_5.jpg
Normal Tissue
Figure 4 Testis
Leydig cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/288/170349_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (NB-4, NTERA-2, SuSa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130234-ACE2
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ACE2
- Host Animal
- Rabbit
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Angiotensin converting enzyme 2
- Biological Process
- Host-virus interaction
- Molecular Function
- Carboxypeptidase, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor
- Introduction
- The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
- Alternative Names
- ACEH
- Gene ID
- 59272
- UniProt ID
- Q9BYF1
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "ACE2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0036 | Hi-Affi™ Rabbit Anti-ACE2 Recombinant Antibody (clone DS36AB) | IHC-P, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0095-CN | Rabbit Anti-ACE2 Recombinant Antibody (clone CBACN-029) | WB, IF, IHC, IP | Rabbit IgG |
| MRO-0050YJ | Rabbit Anti-Human ACE2 Polyclonal Antibody | WB, IHC-P | Rabbit IgG |
| MRO-0098YJ | Rabbit Anti-ACE2 Recombinant Antibody (clone CBA083) | IF, WB | Rabbit IgG |
| MRO-0099YJ | Rabbit Anti-ACE2 Recombinant Antibody (clone CBA084) | IA | Rabbit IgG |
| MRO-0100YJ | Mouse Anti-ACE2 Recombinant Antibody (clone CBA085) | IA | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0097YJ | Mouse Anti-ACE2 Recombinant Antibody (clone CBA082) | WB, ELISA | Mouse IgM, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1513 | Human Anti-ACE2 Recombinant Antibody (VS3-WK1513) | WB, ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC136 | AbPlus™ Anti-ACE2 Magnetic Beads (VS-0724-YC136) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY20 | Anti-ACE2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY73 | Anti-Mouse ACE2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY72 | Anti-Human ACE2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY8 | Human Anti-ACE2 (clone 05B04) scFv-Fc Chimera | FC, Neut, IF, ELISA | Human IgG1, scFv-Fc |
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