Recombinant Anti-ACKR1 Vesicular Antibody, EV Displayed (VS-0425-YC734) (CAT#: VS-0425-YC734)

• Application
• Block, ELISA, FC, SPR, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• ACKR1

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Atypical chemokine receptor 1 (Duffy blood group)

• Molecular Function
• Blood group antigen, G-protein coupled receptor, Receptor, Transducer

• Introduction
• The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene.

• Alternative Names
• CCBP1, CD234, DARC, Dfy, FY, GPD

• Gene ID
• 2532

• UniProt ID
• Q16570

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